Reaction state_transition rc_re245 map

glucose@Cytosol map + ATP@Cytosol map → glucose-6P@Cytosol map + ADP@Cytosol map

Reaction regulators:
Boolean_logic_gate_or
  1. HK1@Cytosol map and and HK3@Cytosol map and GCK@Cytosol map
Catalysis
  1. HK2@Cytosol map
  2. HK1@Cytosol map
  3. HK3@Cytosol map
  4. GCK@Cytosol map
  5. BAD|​S91_unk|​pho:​GCK:​PPP1C*:​PRKAC*:​WASF1@Mitochondrial inner membrane map
Inhibition
  1. glucose-6P@Cytosol map
  2. long-chain acyl-CoAs@Cytosol map


References
PMID:10531306
allosterinc inhibition of HK1 by glucose 6P
PMID:11078441
HK inhibition by long-chain acyl-CoAs
PMID:10760476
PMID:7130182
GCK inhibition by long-chain acyl-CoAs
PMID:12931191
in mouse liver mitochondria GCK activation by phosphorylated BAD within a mitochondrial protein complex