Simple molecule citrate map
citrate@Cytosol

Identifiers
CHEBI:16947 KEGGCOMPOUND:C00158 CAS:126-44-3

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / FERROPTOSIS  map

References
charge:3-
rc_re742:( Regulated Cell Death  map ) PMID:8666394

citrate@Mitochondrial Matrix

Identifiers
CHEBI:16947 KEGGCOMPOUND:C00158 CAS:126-44-3

Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / FERROPTOSIS  map
 Regulated Cell Death  map  / FATTY_ACID_BIOSYNTHESIS  map
 Regulated Cell Death  map  / MITOCHONDRIAL_METABOLISM  map

References
PMID:27048822
PMID:26653790
PMID:26794443
ACSF2 and CS are required for mitochondrial fatty-acid metabolism in ferroptosis.
Knockdown of ACSF2 and CS inhibits erastin-induced ferroptosis
rc_re742:( Regulated Cell Death  map ) PMID:8666394

Modifications:
In compartment: Cytosol
  1. citrate@Cytosol map
In compartment: Mitochondrial Matrix
  1. citrate@Mitochondrial Matrix map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. citrate@Cytosol map → map isocitrate@Cytosol map
    2. citrate@Cytosol map + ATP@Cytosol map + coenzyme A@Cytosol map → map acetyl-CoA@Cytosol map + oxaloacetate@Cytosol map + ADP@Cytosol map
    3. oxaloacetate@Mitochondrial Matrix map + acetyl-CoA@Mitochondrial Matrix map → map citrate@Mitochondrial Matrix map + coenzyme A@Mitochondrial Matrix map
    4. citrate@Mitochondrial Matrix map → map isocitrate@Mitochondrial Matrix map
    5. citrate@Mitochondrial Matrix map → map citrate@Cytosol map
    As Catalyser: