Protein PI3K* map

Identifiers
HUGO:PI3KC
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
HUGO:PIK3CA HGNC:8975 ENTREZ:5290 UNIPROT:P42336

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / DEPENDANCE_RECEPTORS  map

References
PMID:17604717
PMID:24036369
I3K phosphorylates phosphatidylinositol-4,5-bisphosphate (PIP2) to generate phosphatidylinositol-3,4,5-trisphosphate (PIP3), in a reaction that can be reversed by the PIP3 phosphatase PTEN
PMID:22421439
PMID:28645028

PI3K*@Cytosol

References
mo_re190:( motility  map ) PMID:21084277 PMID:19440036 PMID:19945467 PMID:26597054 PMID:17409395 PMID:27328425 PMID:27572739

Modifications:
In compartment: Cytosol
  1. PI3K*@Cytosol map
Participates in complexes:
In compartment: Cytosol
  1. IRS1|​pho:​NGF:​PI3K*:​TrkA*@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. PI3K*@Cytosol map → map PI3K*@Cytosol map
  2. IRS1@Cytosol map + NGF:​TrkA*@Cytosol map + PI3K*@Cytosol map → map IRS1|​pho:​NGF:​PI3K*:​TrkA*@Cytosol map
As Catalyser:
  1. PIP2@Cytosol map → map PIP3@Cytosol map
  2. PIP2*@Cytosol map → map PIP3*@Cytosol map