Complex CNA*:CNB* map
Complex composition:

  1. CNA* map
  2. CNB* map


CNA*:​CNB*@INNATE_IMMUNE_CELL_Cytosol

Identifiers
NAME:CNA*:CNB*

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / IMMUNOSTIMULATORY_CORE_PATHWAYS  map

References
CASCADE:Fc_gamma_RIII
 NATURAL_KILLER  map
PMID:10089876, PMID:7650486, PMID:9973469
??Ca('2+)??activates Calmodulin 2 (??Calmodulin??)/ Protein phosphatase 3 (Calcineurin??) signal. Activated??Calcineurin??dephosphorylates Nuclear factor of activated T-cells cytoplasmic calcineurin-dependent 2 (??NF-AT1(NFATC2)??).??
This signaling is activated downstream of CD16 in NK cells

CNA*:​CNB*@T_cell

Identifiers
NAME:CNA*:CNB*

References
PMID:10089876 PMID:7650486 PMID:9973469

CNA*:​CNB*@Nucleus

Identifiers
NAME:CNA*:CNB*

References
s_wnc3_re31( Survival  map ):
Phosphorylation of NFAT leads to increased DNA binding of NFAT -> increased gene transcription
PMID15657416
Not sure if dissociation of calcineurin and ERK/MEK occurs


Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. CNA*:​CNB*@INNATE_IMMUNE_CELL_Cytosol map
In compartment: Nucleus
  1. CNA*:​CNB*@Nucleus map
In compartment: T_cell
  1. CNA*:​CNB*@T_cell map
Participates in reactions:
As Reactant or Product:
  1. Ca2+:​Calmodulin*@T_cell map + CNA*:​CNB*@T_cell map map CNA*:​CNB*:​Ca2+:​Calmodulin*@T_cell map
  2. Ca2+:​Calmodulin*@INNATE_IMMUNE_CELL_Cytosol map + CNA*:​CNB*@INNATE_IMMUNE_CELL_Cytosol map map CNA*:​CNB*:​Ca2+:​Calmodulin*@INNATE_IMMUNE_CELL_Cytosol map
  3. CNA*:​CNB*:​NFAT*@Nucleus map map CNA*:​CNB*@Nucleus map + NFAT*@Nucleus map
  4. CNA*:​CNB*:​ERK2*:​MEK1*:​NFAT*|​pho@Nucleus map + gAP-1_ARRE binding sites*@Nucleus map + JUN@Nucleus map + FOS@Nucleus map map AP-1_ARRE binding sites*:​NFAT*@Nucleus map + CNA*:​CNB*@Nucleus map + ERK2*@Nucleus map + MEK1*@Nucleus map
As Catalyser: