Complex Ca2+:Calmodulin*
Complex composition:
- Calmodulin*
- Ca2+
Ca2+:Calmodulin*@INNATE_IMMUNE_CELL_Cytosol
Identifiers
NAME:Ca2+:Calmodulin*
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity
/ IMMUNOSTIMULATORY_CORE_PATHWAYS
References
NATURAL_KILLER
CASCADE:Fc_gamma_RIII
PMID:10089876, PMID:7650486, PMID:9973469
??Ca('2+)??activates Calmodulin 2 (??Calmodulin??)/ Protein phosphatase 3 (Calcineurin??) signal. Activated??Calcineurin??dephosphorylates Nuclear factor of activated T-cells cytoplasmic calcineurin-dependent 2 (??NF-AT1(NFATC2)??).??
This signaling is activated downstream of CD16 in NK cells
Ca2+:Calmodulin*@Cytoplasm
Identifiers
NAME:Ca2+:Calmodulin*
Ca2+:Calmodulin*@T_cell
Identifiers
NAME:Ca2+:Calmodulin*
References
PMID:10089876 PMID:7650486 PMID:9973469
Ca2+:Calmodulin*@Nucleus
Identifiers
NAME:Ca2+:Calmodulin*
References
s_wnc3_re10:( Survival
) PMID:22275375, PMID:15657064, PMID:16396959, PMID:16998587
Ca2+:Calmodulin*@Cytoplasm
Identifiers
NAME:Ca2+:Calmodulin*
References
s_wnc1_re160:( Survival
) PMID:19725819
s_wnc2_re7( Survival
):
PMID:17593948
PMID:18235236
Ca2+:Calmodulin*@Cytosol
Identifiers
NAME:Ca2+:Calmodulin*
References
mo_re204:( motility
) PMID:23572150
Modifications:
Participates in complexes:
In compartment: Cytoplasm
- Ca2+:Calmodulin*@Cytoplasm
- Ca2+:Calmodulin*@Cytoplasm
In compartment: Cytosol
- Ca2+:Calmodulin*@Cytosol
In compartment: INNATE_IMMUNE_CELL_Cytosol
- Ca2+:Calmodulin*@INNATE_IMMUNE_CELL_Cytosol
In compartment: Nucleus
- Ca2+:Calmodulin*@Nucleus
In compartment: T_cell
- Ca2+:Calmodulin*@T_cell
Participates in reactions:
As Reactant or Product:- Ca2+@T_cell
+ Calmodulin*@T_cell
→
Ca2+:Calmodulin*@T_cell
- Ca2+:Calmodulin*@T_cell
+ CNA*:CNB*@T_cell
→
CNA*:CNB*:Ca2+:Calmodulin*@T_cell
- Ca2+@INNATE_IMMUNE_CELL_Cytosol
+ Calmodulin*@INNATE_IMMUNE_CELL_Cytosol
→
Ca2+:Calmodulin*@INNATE_IMMUNE_CELL_Cytosol
- Ca2+:Calmodulin*@INNATE_IMMUNE_CELL_Cytosol
+ CNA*:CNB*@INNATE_IMMUNE_CELL_Cytosol
→
CNA*:CNB*:Ca2+:Calmodulin*@INNATE_IMMUNE_CELL_Cytosol
- Ca2+@Cytosol
+ Calmodulin*@Cytosol
→
Ca2+:Calmodulin*@Cytosol
- CAMK2*@Cytosol
+ Ca2+:Calmodulin*@Cytosol
→
CAMK2*:Ca2+:Calmodulin*@Cytosol
- Calmodulin*@Cytoplasm
+ Ca2+@Cytoplasm
→
Ca2+:Calmodulin*@Cytoplasm
- CAMK2*@Cytoplasm
+ Ca2+:Calmodulin*@Cytoplasm
→
CAMK2*:Ca2+:Calmodulin*@Cytoplasm
- PPP3CB:PPP3R*@Cytoplasm
+ Ca2+:Calmodulin*@Cytoplasm
→
Ca2+:Calmodulin*:PPP3CB:PPP3R*@Cytoplasm
As Catalyser:- CAMK2*@T_cell
→
CAMK2*|pho|active@T_cell
- estrogen@Nucleus
+ ER_alpha_*@Nucleus
+ gERE@Nucleus
+ NFAT*@Nucleus
+ FOXA*@Nucleus
→
ERE:ER_alpha_*:FOXA*:NFAT*@Nucleus