Protein CUL2
Identifiers
cullin 2
HUGO:CUL2 HGNC:2552 ENTREZ:8453 UNIPROT:Q13617
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death
/ ANTIOXIDANT_RESPONSE
Regulated Cell Death
/ APOPTOSIS
Regulated Cell Death
/ MOMP_REGULATION
Modifications:
Participates in complexes:
In compartment: Cytosol
- CISH:CUL2:RBX1:TCEB1:TCEB2:TCEB3@Cytosol
- 2-oxoglutarate:CUL2:O_sub_2_endsub_:RACK1*:RBX1:TCEB1:TCEB2:VHL@Cytosol
Participates in reactions:
As Reactant or Product:- HIF1A@Cytosol
+ 2-oxoglutarate:CUL2:O_sub_2_endsub_:RACK1*:RBX1:TCEB1:TCEB2:VHL@Cytosol
+ 2-oxoglutarate:CUL2:O_sub_2_endsub_:RACK1*:RBX1:TCEB1:TCEB2:VHL@Cytosol
→
HIF1A|P564_hyd@Cytosol
+ succinate@Cytosol
+ CO_sub_2_endsub_@Cytosol
As Catalyser:- HIF1A|P564_hyd@Cytosol
→
HIF1A|ubi|P564_hyd@Cytosol
- BimEL*@Cytosol
→
BimEL*|ubi@Cytosol
- BCL2L11|ubi@Cytosol
→
BimEL*|ubi@Cytosol