Reaction state_transition rc_re448 map

BCL2L11|​ubi@Cytosol map → BimEL*|​ubi@Cytosol map

Reaction regulators:
Boolean_logic_gate_and
  1. CISH:​CUL2:​RBX1:​TCEB1:​TCEB2:​TCEB3@Cytosol map and NDRG1@Cytosol map
Catalysis
  1. CISH:​CUL2:​RBX1:​TCEB1:​TCEB2:​TCEB3@Cytosol map
  2. NDRG1@Cytosol map


References
PMID:19622774
BIM interacts with NDRG1 and with CISH and CUL2 in a NDRG1 dependent manner
NDRG1 expression destabilizes BIM