Protein Caspase8* map

Identifiers
caspase 8, apoptosis-related cysteine peptidase
HUGO:CASP8 HGNC:1509 ENTREZ:841 UNIPROT:Q14790
HUGO:CASP8 HGNC:1509 ENTREZ:841 UNIPROT:Q14790 GENECARDS:CASP8 REACTOME:57032 KEGG:841 ATLASONC:GC_CASP8 WIKI:CASP8

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / FAS_RESPONSE  map
 Regulated Cell Death  map  / MOMP_REGULATION  map
 Regulated Cell Death  map  / NECROPTOSIS  map
 Regulated Cell Death  map  / TRAIL_RESPONSE  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / PI3K_AKT_MTOR  map
 Survival  map  / WNT_NON_CANONICAL  map

References
PMID:28462525
PMID:9765224

Caspase8*@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / FAS_RESPONSE  map
 Regulated Cell Death  map  / MOMP_REGULATION  map
 Regulated Cell Death  map  / NECROPTOSIS  map
 Regulated Cell Death  map  / TRAIL_RESPONSE  map

Caspase8*@Cytoplasm

References
s_akt1_re187:( Survival  map ) PMID:9765224
s_wnc4_re39( Survival  map ):
Positive modulaion
PMID:15755874, PMID:23308069

Modifications:
In compartment: Cytoplasm
  1. Caspase8*@Cytoplasm map
  2. Caspase8*@Cytoplasm map
In compartment: Cytosol
  1. Caspase8*@Cytosol map
Participates in complexes:
In compartment: Cytosol
  1. Caspase10*:​Caspase8*@Cytosol map
  2. Caspase8*|​ubi:​FLASH*@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. Caspase8*@Cytosol map → map Caspase8,10*@Cytosol map
  2. Caspase8,10*:​DR4/5*|​gly|​pal@Cytosol map + TRAF2@Cytosol map + IKBKG@Cytosol map + TRADD@Cytosol map + RIPK1@Cytosol map → map Caspase10*:​Caspase8*@Cytosol map
  3. ASK1*:​CFLAR:​Caspase8,10*|​ubi:​DAXX:​FADD:​FAF1:​FASLG:​FAS|​pal:​FLASH*:​RIPK1|​emp|​K377_ubi:​TRAF2@Endosome map → map Caspase8*|​ubi:​FLASH*@Cytosol map
  4. Caspase8*@Cytosol map → map rc_s6308
  5. Caspase8*@Cytosol map → map cleaved~Caspase8*@Cytosol map
  6. rCaspase8*@Nucleus map → map Caspase8*@Cytosol map
  7. Caspase8*@Cytosol map → map cleaved~Caspase8*@Cytosol map
  8. Caspase8*@Cytoplasm map → map Caspase8_sub_TRUNC_endsub_*@Cytoplasm map
As Catalyser:
  1. CHUK:​IKBKG:​IKK_beta_*@TNFRSF1 Receptor Complex map → map CHUK:​IKBKG:​IKK_beta_*|​pho@TNFRSF1 Receptor Complex map
  2. Caspase3*@Cytoplasm map → map Caspase3*@Cytoplasm map