Complex Caspase10*:Caspase8* map
Complex composition:

  1. Caspase8* map
  2. Caspase10* map

Caspase10*:​Caspase8*@Cytosol

Identifiers
NAME:Caspase10*:Caspase8*

References
TRAF2:TRADD:FADD:Caspase8*:Caspase10*:IKBKG:RIPKA
PMID:20531300
The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase
PMID:10958661
PMID:23845861
PMID:21822306
NF-??B exerts a pro-apoptotic role in TRAIL- and CD95-induced apoptosis in glioblastoma cells by facilitating DISC formation
rc_re1654( Regulated Cell Death  map ):
PMID:9430228
TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB.
PMID:16166346
TRAIL promotes cell migration and invasion via a NF-kappaB-dependent pathway in human cholangiocarcinoma cell lines
rc_re1342( Regulated Cell Death  map ):
PMID:11340079
FLASH coordinates NF-kappa B activity via TRAF2

Modifications:
Participates in complexes:
In compartment: Cytosol
  1. Caspase10*:​Caspase8*@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. Caspase8,10*:​DR4/5*|​gly|​pal@Cytosol map + TRAF2@Cytosol map + IKBKG@Cytosol map + TRADD@Cytosol map + RIPK1@Cytosol map → map Caspase10*:​Caspase8*@Cytosol map
As Catalyser:
  1. CHUK:​IKBKG:​IKK_beta_*@TNFRSF1 Receptor Complex map → map CHUK:​IKBKG:​IKK_beta_*|​pho@TNFRSF1 Receptor Complex map