Protein PPP3CB
Identifiers
protein phosphatase 3, catalytic subunit, beta isozyme
HUGO:PPP3CB HGNC:9315 ENTREZ:5532 UNIPROT:P16298
CALNB, "protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform", "protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta)"
HUGO:PPP3CB HGNC:9315 ENTREZ:5532 UNIPROT:P16298 GENECARDS:PPP3CB REACTOME:403037 KEGG:5532 ATLASONC:GC_PPP3CB WIKI:PPP3CB
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death
/ APOPTOSIS
Regulated Cell Death
/ MOMP_REGULATION
HMC:EVADING_GROWTH_SUPPRESSORS
Survival
/ WNT_NON_CANONICAL
Modifications:
Participates in complexes:
In compartment: Cytoplasm
- PPP3CB:PPP3R*@Cytoplasm
- PPP3CB|ubi|ubi|ubi:PPP3R*@Cytoplasm
- CAIN*:PPP3CB:PPP3R*@Cytoplasm
- PPP3CB:PPP3R*:RCAN*|T192_pho@Cytoplasm
- Ca2+:Calmodulin*:PPP3CB:PPP3R*@Cytoplasm
- Ca2+:Calmodulin*:NFAT*:PPP3CB:PPP3R*@Cytoplasm
- Ca2+:Calmodulin*:NFAT*|pho|pho|pho|pho|pho|pho|pho|pho|pho|pho|pho|pho|pho|pho:PPP3CB:PPP3R*@Cytoplasm
- Ca2+:Calmodulin*:KPNB1:NFAT*:PPP3CB:PPP3R*:TNPO1:Tubulin-_alpha_*@Cytoplasm
- CSE1L:Ca2+:Calmodulin*:KPNB1:LRRK2:NFAT*:NRON:PPP3CB:PPP3R*:TNPO1:Tubulin-_alpha_*@Cytoplasm
In compartment: Cytosol
- PPP3CB:PPP3R1@Cytosol
In compartment: Nucleus
- Ca2+:Calmodulin*:PPP3CB:PPP3R*@Nucleus
- Ca2+:Calmodulin*:KPNB1:NFAT*:PPP3CB:PPP3R*:Tubulin-_alpha_*@Nucleus
Participates in reactions:
As Reactant or Product:- PPP3CB:PPP3R*@Cytoplasm
+ CAIN*@Cytoplasm
→
CAIN*:PPP3CB:PPP3R*@Cytoplasm
- Ca2+:Calmodulin*:PPP3CB:PPP3R*@Cytoplasm
+ NFAT*|pho|pho|pho|pho|pho|pho|pho|pho|pho|pho|pho|pho|pho|pho@Cytoplasm
→
Ca2+:Calmodulin*:NFAT*|pho|pho|pho|pho|pho|pho|pho|pho|pho|pho|pho|pho|pho|pho:PPP3CB:PPP3R*@Cytoplasm
- Ca2+:Calmodulin*:NFAT*|pho|pho|pho|pho|pho|pho|pho|pho|pho|pho|pho|pho|pho|pho:PPP3CB:PPP3R*@Cytoplasm
→
Ca2+:Calmodulin*:NFAT*:PPP3CB:PPP3R*@Cytoplasm
- Ca2+:Calmodulin*:KPNB1:NFAT*:PPP3CB:PPP3R*:TNPO1:Tubulin-_alpha_*@Cytoplasm
→
Ca2+:Calmodulin*:KPNB1:NFAT*:PPP3CB:PPP3R*:Tubulin-_alpha_*@Nucleus
- Ca2+:Calmodulin*:NFAT*:PPP3CB:PPP3R*@Cytoplasm
+ KPNB1@Cytoplasm
+ Tubulin-_alpha_*@Cytoplasm
+ TNPO1@Cytoplasm
→
Ca2+:Calmodulin*:KPNB1:NFAT*:PPP3CB:PPP3R*:TNPO1:Tubulin-_alpha_*@Cytoplasm
- Ca2+:Calmodulin*:KPNB1:NFAT*:PPP3CB:PPP3R*:TNPO1:Tubulin-_alpha_*@Cytoplasm
+ LRRK2@Cytoplasm
+ rNRON@Cytoplasm
+ CSE1L@Cytoplasm
→
CSE1L:Ca2+:Calmodulin*:KPNB1:LRRK2:NFAT*:NRON:PPP3CB:PPP3R*:TNPO1:Tubulin-_alpha_*@Cytoplasm
- Ca2+:Calmodulin*:PPP3CB:PPP3R*@Cytoplasm
→
Ca2+:Calmodulin*:PPP3R*@Cytoplasm
- PPP3CB:PPP3R*@Cytoplasm
+ RCAN*|T192_pho@Cytoplasm
→
PPP3CB:PPP3R*:RCAN*|T192_pho@Cytoplasm
- Ca2+:Calmodulin*:KPNB1:NFAT*:PPP3CB:PPP3R*:Tubulin-_alpha_*@Nucleus
→
NFAT*@Nucleus
+ Tubulin-_alpha_*@Nucleus
+ Ca2+:Calmodulin*:PPP3CB:PPP3R*@Nucleus
+ KPNB1@Nucleus
- PPP3CB:PPP3R*@Cytoplasm
→
PPP3CB|ubi|ubi|ubi:PPP3R*@Cytoplasm
- PPP3CB|ubi|ubi|ubi:PPP3R*@Cytoplasm
→
degraded
- PPP3CB:PPP3R*@Cytoplasm
+ Ca2+:Calmodulin*@Cytoplasm
→
Ca2+:Calmodulin*:PPP3CB:PPP3R*@Cytoplasm
- PPP3CB:PPP3R*@Cytoplasm
→
(PPP3CB_sub_trunc_endsub_*:PPP3R*)|active@Cytoplasm
As Catalyser:- BAD|pho@Cytosol
→
BAD@Cytosol
- 14-3-3*:BAD|pho|pho|pho@Cytoplasm
→
14-3-3*:BAD|pho|pho@Cytoplasm
- TAB1:TAB2:TAK1*|pho@Cytoplasm
→
TAB1:TAB2:TAK1*|emp@Cytoplasm
- MEF2*|pho|pho|pho|pho|pho|pho@Cytoplasm
→
MEF2*@Cytoplasm