Protein LRRK2 map

Identifiers
leucine-rich repeat kinase 2
HUGO:LRRK2 HGNC:18618 ENTREZ:120892 UNIPROT:Q5S007 GENECARDS:LRRK2 KEGG:120892 ATLASONC:GC_LRRK2 WIKI:LRRK2

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_NON_CANONICAL  map

LRRK2@Cytoplasm

References
s_wnc2_re47( Survival  map ):
LRKK2 mediates binding of NFAT to NRON and other components, but this is independent of its kinase activity and independent of the phosphorylation status of NFAT
PMID:21983832
s_wnc2_re48:( Survival  map ) PMID:21709260

Modifications:
In compartment: Cytoplasm
  1. LRRK2@Cytoplasm map
Participates in complexes:
In compartment: Cytoplasm
  1. CSE1L:​KPNB1:​LRRK2:​NFAT*:​NRON:​PPP3CB_sub_trunc_endsub_*:​PPP3R*:​TNPO1:​Tubulin-_alpha_*@Cytoplasm map
  2. CSE1L:​Ca2+:​Calmodulin*:​KPNB1:​LRRK2:​NFAT*:​NRON:​PPP3CB:​PPP3R*:​TNPO1:​Tubulin-_alpha_*@Cytoplasm map
Participates in reactions:
As Reactant or Product:
  1. Ca2+:​Calmodulin*:​KPNB1:​NFAT*:​PPP3CB:​PPP3R*:​TNPO1:​Tubulin-_alpha_*@Cytoplasm map + LRRK2@Cytoplasm map + rNRON@Cytoplasm map + CSE1L@Cytoplasm map → map CSE1L:​Ca2+:​Calmodulin*:​KPNB1:​LRRK2:​NFAT*:​NRON:​PPP3CB:​PPP3R*:​TNPO1:​Tubulin-_alpha_*@Cytoplasm map
  2. KPNB1:​NFAT*:​PPP3CB_sub_trunc_endsub_*:​PPP3R*:​TNPO1:​Tubulin-_alpha_*@Cytoplasm map + LRRK2@Cytoplasm map + CSE1L@Cytoplasm map + rNRON@Cytoplasm map → map CSE1L:​KPNB1:​LRRK2:​NFAT*:​NRON:​PPP3CB_sub_trunc_endsub_*:​PPP3R*:​TNPO1:​Tubulin-_alpha_*@Cytoplasm map
As Catalyser:
  1. Ca2+:​Calmodulin*:​KPNB1:​NFAT*:​PPP3CB:​PPP3R*:​TNPO1:​Tubulin-_alpha_*@Cytoplasm map + LRRK2@Cytoplasm map + rNRON@Cytoplasm map + CSE1L@Cytoplasm map → map CSE1L:​Ca2+:​Calmodulin*:​KPNB1:​LRRK2:​NFAT*:​NRON:​PPP3CB:​PPP3R*:​TNPO1:​Tubulin-_alpha_*@Cytoplasm map
  2. KPNB1:​NFAT*:​PPP3CB_sub_trunc_endsub_*:​PPP3R*:​TNPO1:​Tubulin-_alpha_*@Cytoplasm map + LRRK2@Cytoplasm map + CSE1L@Cytoplasm map + rNRON@Cytoplasm map → map CSE1L:​KPNB1:​LRRK2:​NFAT*:​NRON:​PPP3CB_sub_trunc_endsub_*:​PPP3R*:​TNPO1:​Tubulin-_alpha_*@Cytoplasm map