Identifiers
CSE1 chromosome segregation 1-like (yeast)
HUGO:CSE1L HGNC:2431 ENTREZ:1434 UNIPROT:P55060
"chromosome segregation 1 (yeast homolog)-like"
HUGO:CSE1L HGNC:2431 ENTREZ:1434 UNIPROT:P55060 GENECARDS:CSE1L KEGG:1434 ATLASONC:CSE1LID40159ch20q13 WIKI:CSE1L
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death / APOPTOSIS
Regulated Cell Death / CASPASES
HMC:EVADING_GROWTH_SUPPRESSORS
Survival / WNT_NON_CANONICAL
References
synonym:CAS
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death / APOPTOSIS
Regulated Cell Death / CASPASES
References
rc_re482( Regulated Cell Death ):
PMID:17377525
review on apoptosome formation
PMID:11864614
stoechiometry apoptosome
PMID:12522243
inhibition of apoptosome formation by prothymosin-alpha
PMID:15087373
in HT-29 colon adenocarcinoma cells, siRNA against ACHE prevents the APAF1:CYCS interaction and etoposide-induced
PMID:14622304
AFP positive influence on apoptosome assembly
PMID:18439902
CAS PHAPI and HSP70 enhance apoptosome formation and caspase activation
References
s_wnc2_re47( Survival ):
LRKK2 mediates binding of NFAT to NRON and other components, but this is independent of its kinase activity and independent of the phosphorylation status of NFAT
PMID:21983832
s_wnc2_re48:( Survival ) PMID:21709260
+ LRRK2@Cytoplasm + rNRON@Cytoplasm + CSE1L@Cytoplasm → CSE1L:Ca2+:Calmodulin*:KPNB1:LRRK2:NFAT*:NRON:PPP3CB:PPP3R*:TNPO1:Tubulin-_alpha_*@Cytoplasm
+ LRRK2@Cytoplasm + CSE1L@Cytoplasm + rNRON@Cytoplasm → CSE1L:KPNB1:LRRK2:NFAT*:NRON:PPP3CB_sub_trunc_endsub_*:PPP3R*:TNPO1:Tubulin-_alpha_*@Cytoplasm