Complex AMER1*:APC:AXIN*:CK1_alpha_*:GSK3*:PtdIns(4,5)-P2 map
Complex composition:

  1. AXIN* map
  2. APC map
  3. CK1_alpha_* map
  4. GSK3* map
  5. PtdIns(4,5)-P2 map
  6. AMER1* map

AMER1*:​APC:​AXIN*:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2@Cytoplasm

Identifiers
NAME:AMER1*:APC:AXIN*:CK1_alpha_*:GSK3*:PtdIns

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_CANONICAL  map

References
PMID:17143292
s_wca1_re19:( Survival  map ) PMID:17318175
s_wca1_re34( Survival  map ):
PMID:21498506
Membrane-bound AMER1 acts as scaffold and brings APC to the membrane

AMER1*:​APC:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho|​S614_pho|​S621_pho:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2@Cytoplasm

Identifiers
NAME:AMER1*:APC:AXIN*:CK1_alpha_*:GSK3*:PtdIns

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_CANONICAL  map

References
PMID:17143292
s_wca1_re15:( Survival  map ) PMID:10581160

AMER1*:​APC:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho|​S614_emp|​S621_pho:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2@Cytoplasm

Identifiers
NAME:AMER1*:APC:AXIN*:CK1_alpha_*:GSK3*:PtdIns

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_CANONICAL  map

References
PMID:17143292
s_wca1_re12:( Survival  map ) PMID:10581160

AMER1*:​APC:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2@Cytoplasm

Identifiers
NAME:AMER1*:APC:AXIN*:CK1_alpha_*:GSK3*:PtdIns

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_CANONICAL  map

References
PMID:17143292
s_wca1_re12:( Survival  map ) PMID:10581160
s_wca1_re16:( Survival  map ) PMID:17318175 PMID:19581931

Modifications:
Participates in complexes:
In compartment: Cytoplasm
  1. AMER1*:​APC:​AXIN*:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2@Cytoplasm map
  2. AMER1*:​APC:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2@Cytoplasm map
  3. AMER1*:​APC:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho|​S614_emp|​S621_pho:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2@Cytoplasm map
  4. AMER1*:​APC:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho|​S614_pho|​S621_pho:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2@Cytoplasm map
Participates in reactions:
As Reactant or Product:
  1. AMER1*:​APC:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho|​S614_pho|​S621_pho:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2@Cytoplasm map + _beta_-Catenin*@Cytoplasm map → map AMER1*:​APC:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho|​S614_pho|​S621_pho:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2:​_beta_-Catenin*@Cytoplasm map
  2. AMER1*:​APC:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2@Cytoplasm map → map AMER1*:​APC:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho|​S614_emp|​S621_pho:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2@Cytoplasm map
  3. AMER1*:​APC:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho|​S614_emp|​S621_pho:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2@Cytoplasm map → map AMER1*:​APC:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho|​S614_pho|​S621_pho:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2@Cytoplasm map
  4. AMER1*:​APC:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2@Cytoplasm map + PPP1C*:​PPP1R*@Cytoplasm map → map AMER1*:​APC:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho:​CK1_alpha_*:​GSK3*:​PPP1C*:​PPP1R*@Cytoplasm map
  5. APC:​AXIN*|​S80_emp|​S82_emp|​S222_emp|​S473_emp:​CK1_alpha_*:​GSK3*:​PPP1C*:​PPP1R*@Cytoplasm map → map GSK3*@Cytoplasm map + AMER1*:​APC:​AXIN*:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2@Cytoplasm map + PPP1C*:​PPP1R*@Cytoplasm map
  6. APC:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho|​S614_pho|​S621_pho:​CK1_alpha_*:​GSK3*:​PP2A_C*:​PR55_alpha_*:​PR65_A*:​_beta_-Catenin*|​S45_emp|​T41_emp|​S37_emp|​S33_emp@Cytoplasm map → map PP2A_C*:​PR55_alpha_*:​PR65_A*@Cytoplasm map + _beta_-Catenin*@Cytoplasm map + AMER1*:​APC:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho|​S614_pho|​S621_pho:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2@Cytoplasm map
  7. AXIN*:​CK1_alpha_*:​GSK3*@Cytoplasm map + APC@Cytoplasm map + AMER1*@Cytoplasm map → map AMER1*:​APC:​AXIN*:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2@Cytoplasm map
  8. AMER1*:​APC:​AXIN*:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2@Cytoplasm map → map AMER1*:​APC:​AXIN*|​S80_pho|​S82_pho|​S222_pho|​S473_pho:​CK1_alpha_*:​GSK3*:​PtdIns(4,5)-P2@Cytoplasm map
As Catalyser: