Reaction heterodimer_association su_wca1_s_wca1_re34
AXIN*:CK1_alpha_*:GSK3*@Cytoplasm
+ APC@Cytoplasm
+ AMER1*@Cytoplasm
→ AMER1*:APC:AXIN*:CK1_alpha_*:GSK3*:PtdIns(4,5)-P2@Cytoplasm
No reaction regulators
Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
Survival
/ WNT_CANONICAL
References
PMID:21498506
Membrane-bound AMER1 acts as scaffold and brings APC to the membrane