Protein KDR map

Identifiers
HGNC:6307
HUGO:KDR

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
 Innate Immunity  map  / IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS  map

References
PMID:16076871
 DENDRITIC_CELL  map
CASCADE:VEGFA
PMID:17086423
Vascular endothelial growth factor inhibits the function of
human mature dendritic cells mediated by VEGF receptor-2 (KDR)
VEGF treatment enhanced the phospho-Erk 1 and 2 via KDR.
PMID:17883421

KDR@Cytosol

References
an_re9:( Angiogenesis  map ) PMID:25922287

Modifications:
In compartment: Cytosol
  1. KDR@Cytosol map
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. KDR@INNATE_IMMUNE_CELL_Membrane map
In compartment: Membrane
  1. KDR@Membrane map
Participates in complexes:
In compartment: Cytosol
  1. FIGF:​KDR:​NRP1:​VEGFC@Cytosol map
  2. KDR|​Y1175_emp|​1054_pho:​NRP1:​VEGFA:​VEGFB@Cytosol map
  3. GRB2:​KDR|​Y1175_pho|​1054_pho:​NCK1:​NRP1:​SHC1:​SHP1*:​SHP2*:​VEGFA:​VEGFB@Cytosol map
  4. CRK:​CRKL:​FIGF:​FLT4|​Y1230_pho|​Y1063_pho:​KDR|​Y1175_emp|​1054_pho:​NRP1:​NRP2:​VEGFA:​VEGFB:​VEGFC@Cytosol map
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. KDR:​VEGFA@INNATE_IMMUNE_CELL_Membrane map
In compartment: Membrane
  1. KDR:​VEGF*@Membrane map
Participates in reactions:
As Reactant or Product:
  1. FIGF:​KDR:​NRP1:​VEGFC@Cytosol map → map KDR|​Y1175_emp|​1054_pho:​NRP1:​VEGFA:​VEGFB@Cytosol map
  2. KDR|​Y1175_emp|​1054_pho:​NRP1:​VEGFA:​VEGFB@Cytosol map + GRB2@Extracellular Matrix map + SHP1*@Extracellular Matrix map + NCK1@Extracellular Matrix map + SHC1@Extracellular Matrix map + SHP2*@Extracellular Matrix map → map GRB2:​KDR|​Y1175_pho|​1054_pho:​NCK1:​NRP1:​SHC1:​SHP1*:​SHP2*:​VEGFA:​VEGFB@Cytosol map
  3. GRB2:​KDR|​Y1175_pho|​1054_pho:​NCK1:​NRP1:​SHC1:​SHP1*:​SHP2*:​VEGFA:​VEGFB@Cytosol map → map FAK*@Cytosol map
  4. GRB2:​KDR|​Y1175_pho|​1054_pho:​NCK1:​NRP1:​SHC1:​SHP1*:​SHP2*:​VEGFA:​VEGFB@Cytosol map → map GRB2:​SHC1:​SOS*@Cytosol map
  5. FIGF:​KDR:​NRP1:​VEGFC@Cytosol map + FIGF:​FLT4:​NRP2:​VEGFC@Cytosol map + CRKL@Cytosol map + CRK@Cytosol map + VEGFA:​VEGFB@Extracellular Matrix map → map CRK:​CRKL:​FIGF:​FLT4|​Y1230_pho|​Y1063_pho:​KDR|​Y1175_emp|​1054_pho:​NRP1:​NRP2:​VEGFA:​VEGFB:​VEGFC@Cytosol map
  6. GRB2:​KDR|​Y1175_pho|​1054_pho:​NCK1:​NRP1:​SHC1:​SHP1*:​SHP2*:​VEGFA:​VEGFB@Cytosol map → map PKC activation@Cytosol map
  7. GRB2:​KDR|​Y1175_pho|​1054_pho:​NCK1:​NRP1:​SHC1:​SHP1*:​SHP2*:​VEGFA:​VEGFB@Cytosol map → map p38*@Cytosol map
  8. GRB2:​KDR|​Y1175_pho|​1054_pho:​NCK1:​NRP1:​SHC1:​SHP1*:​SHP2*:​VEGFA:​VEGFB@Cytosol map → map PKC activation@Cytosol map
  9. FIGF:​VEGFC@Extracellular Matrix map + NRP1@Extracellular Matrix map + KDR@Cytosol map → map FIGF:​KDR:​NRP1:​VEGFC@Cytosol map
  10. KDR@INNATE_IMMUNE_CELL_Membrane map + VEGFA@default map → map KDR:​VEGFA@INNATE_IMMUNE_CELL_Membrane map
  11. KDR@Membrane map + VEGF*@Membrane map → map KDR:​VEGF*@Membrane map
  12. KDR:​VEGF*@Membrane map → map PI3K_PATHWAY@Membrane map
  13. KDR:​VEGF*@Membrane map → map PLCG_PATHWAYS@Membrane map
As Catalyser:
  1. SYK@Cytosol map → map SYK|​pho@Cytosol map
  2. PIK3R1:​PIK3R2@Cytosol map → map PIK3R1|​pho:​PIK3R2@Cytosol map
  3. PLCG1@Cytosol map → map PLCG1|​pho@Cytosol map
  4. FAK*@Cytosol map → map FAK*|​pho@Cytosol map
  5. FYN@Cytosol map → map FYN|​pho@Cytosol map
  6. ERK1/2*@INNATE_IMMUNE_CELL_Cytosol map → map ERK1/2*|​pho@INNATE_IMMUNE_CELL_Cytosol map