Phenotype Persistant ER Stress
Persistant ER Stress@Endopasmic Reticulum
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death
/ ER_STRESS
References
PMID:26587781
PMID:17991856
Modifications:
In compartment: Endopasmic Reticulum
- Persistant ER Stress@Endopasmic Reticulum
Participates in complexes:
Participates in reactions:
As Reactant or Product:- ER Stress@Endopasmic Reticulum
→
Persistant ER Stress@Endopasmic Reticulum
- Persistant ER Stress@Endopasmic Reticulum
→
adaptative response@Cytosol
As Catalyser:- IRE1-alpha*:Unfolded protein*@Endopasmic Reticulum
+ TRAF2@Cytosol
→
MCL1|pho|hm2:TRAF2:Unfolded protein*@Endopasmic Reticulum
- gCHOP*@Nucleus
→
rCHOP*@Nucleus
- PERK*@Endopasmic Reticulum
→
rc_s267
- rc_s7531 + SQSTM1 @Autophgosome
+ LC3*@Autophgosome
+ ATG5@Autophgosome
→
ATG5:CASP8|K63_ubi:FADD:LC3*:SQSTM1 @Autophgosome
- IRE1-alpha*@Endopasmic Reticulum
+ BCL2L11@Endopasmic Reticulum
→
BCL2L11:IRE1-alpha*@Endopasmic Reticulum
- IRE1-alpha*@Endopasmic Reticulum
+ BBC3@Endopasmic Reticulum
→
BBC3:IRE1-alpha*@Endopasmic Reticulum