Complex BBC3:IRE1-alpha*
Complex composition:
- BBC3
- IRE1-alpha*
BBC3:IRE1-alpha*@Endopasmic Reticulum
Identifiers
NAME:BBC3:IRE1-alpha*
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death
/ ER_STRESS
References
PMID:23430059
Under mild ER stress BH3-only proteins Bim and PUMA bind IRE1a, via their BH3 domain, and stimulate its RNase activity
Modifications:
Participates in complexes:
In compartment: Endopasmic Reticulum
- BBC3:IRE1-alpha*@Endopasmic Reticulum
Participates in reactions:
As Reactant or Product:- IRE1-alpha*@Endopasmic Reticulum
+ BBC3@Endopasmic Reticulum
→
BBC3:IRE1-alpha*@Endopasmic Reticulum
As Catalyser:- ruXBP1@Nucleus
→
rsXBP1@Nucleus