Protein ATG5
Identifiers
autophagy related 5
HUGO:ATG5 HGNC:589 ENTREZ:9474 UNIPROT:Q9H1Y0
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death
/ STARVATION_AUTOPHAGY
Regulated Cell Death
/ CASPASES
Regulated Cell Death
/ DEATH_RECEPTOR_PATHWAYS
Regulated Cell Death
/ RCD_GENES
References
PMID:23725295
ATG5@Autopagosome
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death
/ STARVATION_AUTOPHAGY
Regulated Cell Death
/ CASPASES
Regulated Cell Death
/ DEATH_RECEPTOR_PATHWAYS
Regulated Cell Death
/ RCD_GENES
ATG5@Cytosol
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death
/ STARVATION_AUTOPHAGY
Regulated Cell Death
/ CASPASES
Regulated Cell Death
/ DEATH_RECEPTOR_PATHWAYS
Regulated Cell Death
/ RCD_GENES
ATG5@Autophgosome
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death
/ STARVATION_AUTOPHAGY
Regulated Cell Death
/ CASPASES
Regulated Cell Death
/ DEATH_RECEPTOR_PATHWAYS
Regulated Cell Death
/ RCD_GENES
Modifications:
In compartment: Autopagosome
- ATG5@Autopagosome
In compartment: Autophgosome
- ATG5@Autophgosome
In compartment: Cytosol
- ATG5@Cytosol
Participates in complexes:
In compartment: Autopagosome
- ATG12:ATG5@Autopagosome
- ATG12:ATG16*:ATG5@Autopagosome
- ATG5:Caspase8,10*|ubi:FADD@Autopagosome
In compartment: Autophgosome
- ATG5:CASP8|K63_ubi:FADD:LC3*:SQSTM1 @Autophgosome
Participates in reactions:
As Reactant or Product:- ATG12@Autopagosome
+ ATG5@Autopagosome
→
ATG12:ATG5@Autopagosome
- ATG12:ATG5@Autopagosome
+ ATG16*@Autopagosome
→
ATG12:ATG16*:ATG5@Autopagosome
- ATG5@Autopagosome
+ FADD@Cytosol
+ Caspase8,10*|ubi|active@Cytosol
→
ATG5:Caspase8,10*|ubi:FADD@Autopagosome
- ATG5@Autopagosome
→
ATG5@Cytosol
- ATG5@Cytosol
→
Cleaved ATG5*@Cytosol
- rATG5@Nucleus
→
ATG5@Cytosol
- rc_s7531 + SQSTM1 @Autophgosome
+ LC3*@Autophgosome
+ ATG5@Autophgosome
→
ATG5:CASP8|K63_ubi:FADD:LC3*:SQSTM1 @Autophgosome
- ATG5:CASP8|K63_ubi:FADD:LC3*:SQSTM1 @Autophgosome
→
Apoptosis@Cytosol
As Catalyser:- LC3-I*@Cytosol
→
LC3-I*@Autopagosome
- ATG3:LC3-I*@Autopagosome
+ Phosphatidyl ethanolamine@Autopagosome
→
ATG3:LC3-I*:Phosphatidyl ethanolamine@Autopagosome
- Caspase8*@Cytosol
→
cleaved~Caspase8*@Cytosol
- Caspase10*@Cytosol
→
cleaved Caspase 10*@Cytosol