Protein RICTOR map

Identifiers
HUGO:RICTOR
RPTOR independent companion of MTOR, complex 2
HUGO:RICTOR HGNC:28611 ENTREZ:253260 UNIPROT:Q6R327
HUGO:RICTOR HGNC:28611 ENTREZ:253260 UNIPROT:Q6R327 GENECARDS:RICTOR REACTOME:245693 KEGG:253260 ATLASONC:GC_RICTOR WIKI:RICTOR

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Adaptive Immune Response  map  / TCR_SIGNALING  map
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / MOMP_REGULATION  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / PI3K_AKT_MTOR  map

References
PMID:16469695 PMID:26159692
PMID:19143635

RICTOR@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / MOMP_REGULATION  map

References
rc_re1038( Regulated Cell Death  map ):
influenceDelete: re to reactants
engagement of mTOR in mTORC2 does not titrate it out of mTORC1

RICTOR|​T1135_pho@Cytoplasm

References
s_akt1_re200:( Survival  map ) PMID:20832730

Modifications:
In compartment: Cytoplasm
  1. RICTOR|​T1135_pho@Cytoplasm map
In compartment: Cytosol
  1. RICTOR@Cytosol map
Participates in complexes:
In compartment: Cytoplasm
  1. 14-3-3*:​RICTOR|​T1135_pho@Cytoplasm map
  2. CUL1:​RBX1:​RICTOR@Cytoplasm map
  3. CUL1:​RBX1:​RICTOR|​T1135_pho@Cytoplasm map
  4. MAPKAP1:​MLST8:​MTOR:​PROTOR*:​RAC1:​RICTOR@Cytoplasm map
  5. 14-3-3*:​MAPKAP1:​MLST8:​MTOR:​PROTOR*:​RICTOR|​T1135_pho@Cytoplasm map
In compartment: Cytosol
  1. MAPKAP1:​RICTOR@Cytosol map
  2. DEPDC6:​MAPKAP1:​RICTOR@Cytosol map
In compartment: Lipid Raft
  1. MAPKAP1:​MLST8:​MTOR|​S2481_pho:​PROTOR*:​RAC1:​RICTOR@Lipid Raft map
  2. MAPKAP1:​MLST8:​MTOR|​S2481_pho:​PROTOR*:​RAC1:​RICTOR|​T1135_pho@Lipid Raft map
  3. DEPTOR:​MAPKAP1:​MLST8:​MTOR|​S2481_pho:​PROTOR*:​RAC1:​RICTOR@Lipid Raft map
  4. 14-3-3*:​MAPKAP1:​MLST8:​MTOR|​S2481_pho:​PROTOR*:​RAC1:​RICTOR|​T1135_pho@Lipid Raft map
In compartment: T_cell
  1. MAPKAP1:​MLST8:​MTOR:​PRR5:​RICTOR@T_cell map
Participates in reactions:
As Reactant or Product:
  1. MAPKAP1@Cytosol map + RICTOR@Cytosol map + MLST8@Cytosol map + MTOR@Cytosol map → map MAPKAP1:​RICTOR@Cytosol map
  2. MAPKAP1:​RICTOR@Cytosol map + DEPDC6@Cytosol map → map DEPDC6:​MAPKAP1:​RICTOR@Cytosol map
  3. DEPTOR@Cytoplasm map + MAPKAP1:​MLST8:​MTOR|​S2481_pho:​PROTOR*:​RAC1:​RICTOR@Lipid Raft map → map DEPTOR:​MAPKAP1:​MLST8:​MTOR|​S2481_pho:​PROTOR*:​RAC1:​RICTOR@Lipid Raft map
  4. 14-3-3*:​MAPKAP1:​MLST8:​MTOR|​S2481_pho:​PROTOR*:​RAC1:​RICTOR|​T1135_pho@Lipid Raft map → map 14-3-3*:​MAPKAP1:​MLST8:​MTOR:​PROTOR*:​RICTOR|​T1135_pho@Cytoplasm map
  5. MAPKAP1:​MLST8:​MTOR:​PROTOR*:​RAC1:​RICTOR@Cytoplasm map → map MAPKAP1:​MLST8:​MTOR|​S2481_pho:​PROTOR*:​RAC1:​RICTOR@Lipid Raft map
  6. CUL1:​RBX1:​RICTOR@Cytoplasm map → map CUL1:​RBX1:​RICTOR|​T1135_pho@Cytoplasm map
  7. CUL1:​RBX1:​RICTOR|​T1135_pho@Cytoplasm map → map RICTOR|​T1135_pho@Cytoplasm map + CUL1@Cytoplasm map + RBX1@Cytoplasm map
  8. 14-3-3*@Cytoplasm map + RICTOR|​T1135_pho@Cytoplasm map → map 14-3-3*:​RICTOR|​T1135_pho@Cytoplasm map
  9. MAPKAP1:​MLST8:​MTOR|​S2481_pho:​PROTOR*:​RAC1:​RICTOR@Lipid Raft map → map MAPKAP1:​MLST8:​MTOR|​S2481_pho:​PROTOR*:​RAC1:​RICTOR|​T1135_pho@Lipid Raft map
  10. MAPKAP1:​MLST8:​MTOR|​S2481_pho:​PROTOR*:​RAC1:​RICTOR|​T1135_pho@Lipid Raft map + 14-3-3*@Lipid Raft map → map 14-3-3*:​MAPKAP1:​MLST8:​MTOR|​S2481_pho:​PROTOR*:​RAC1:​RICTOR|​T1135_pho@Lipid Raft map
As Catalyser:
  1. AKT*@T_cell map → map AKT*|​Thr450_pho@T_cell map
  2. AKT*|​Thr308_pho|​Thr450_pho@T_cell map → map AKT*|​Thr308_pho|​ser473_pho|​Thr450_pho|​active@T_cell map
  3. DEPDC6@Cytosol map → map DEPDC6|​pho@Cytosol map
  4. AKT*@Cytosol map → map AKT*|​S473_pho|​T308_pho@Cytosol map
  5. SGK1@Cytoplasm map → map SGK1|​ubi@Cytoplasm map
  6. AKT1|​T308_pho|​T450_pho|​S473_emp:​PI3,4,5-P3@Lipid Raft map → map AKT1|​T308_pho|​T450_pho|​S473_pho:​PI3,4,5-P3@Lipid Raft map
  7. AKT1|​T450_emp|​S473_emp|​S129_emp@Cytoplasm map → map AKT1|​T450_pho|​S473_emp|​active@Cytoplasm map
  8. SGK1@Cytoplasm map → map SGK1|​S442_pho@Cytoplasm map