Protein DEPTOR map

Identifiers
HUGO:DEPTOR
DEP domain containing MTOR-interacting protein
HUGO:DEPTOR HGNC:22953 ENTREZ:64798 UNIPROT:Q8TB45 GENECARDS:DEPTOR KEGG:64798 ATLASONC:GC_DEPTOR WIKI:DEPTOR

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / CORE  map
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / IMMUNOSTIMULATORY_CORE_PATHWAYS  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / PI3K_AKT_MTOR  map

References
PMID:16469695 PMID:26159692 PMID:23087689
PMID:16469695, PMID:26159692
mTOR Complex 1 (mTORC1) is composed of mTOR itself, regulatory-associated protein of mTOR (Raptor), mammalian lethal with SEC13 protein 8 (MLST8) and the recently identified PRAS40 and DEPTOR
 NATURAL_KILLER  map
 DENDRITIC_CELL  map
PMID:19446321
PMID:19706736

Modifications:
In compartment: Cytoplasm
  1. DEPTOR@Cytoplasm map
Participates in complexes:
In compartment: Cytosol
  1. DEPTOR:​MLST8:​MTOR:​PRAS40*:​RPTOR@Cytosol map
  2. (DEPTOR:​MLST8:​MTOR|​pho:​PRAS40*:​RPTOR)|​active@Cytosol map
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. DEPTOR:​MLST8:​MTOR:​PRAS40*:​RPTOR@INNATE_IMMUNE_CELL_Cytosol map
  2. (DEPTOR:​MLST8:​MTOR|​pho:​PRAS40*:​RPTOR)|​active@INNATE_IMMUNE_CELL_Cytosol map
In compartment: Lipid Raft
  1. DEPTOR:​MAPKAP1:​MLST8:​MTOR|​S2481_pho:​PROTOR*:​RAC1:​RICTOR@Lipid Raft map
In compartment: Membrane Lysosome
  1. DEPTOR:​MLST8:​MTOR|​S1261_pho|​emp|​S2481_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map
In compartment: T_cell
  1. DEPTOR:​MLST8:​MTOR:​PRAS40*:​RPTOR@T_cell map
  2. (DEPTOR:​MLST8:​MTOR|​pho:​PRAS40*:​RPTOR)|​active@T_cell map
Participates in reactions:
As Reactant or Product:
  1. DEPTOR:​MLST8:​MTOR:​PRAS40*:​RPTOR@T_cell map → map (DEPTOR:​MLST8:​MTOR|​pho:​PRAS40*:​RPTOR)|​active@T_cell map
  2. DEPTOR:​MLST8:​MTOR:​PRAS40*:​RPTOR@Cytosol map → map (DEPTOR:​MLST8:​MTOR|​pho:​PRAS40*:​RPTOR)|​active@Cytosol map
  3. DEPTOR:​MLST8:​MTOR:​PRAS40*:​RPTOR@INNATE_IMMUNE_CELL_Cytosol map → map (DEPTOR:​MLST8:​MTOR|​pho:​PRAS40*:​RPTOR)|​active@INNATE_IMMUNE_CELL_Cytosol map
  4. DEPTOR@Cytoplasm map + MAPKAP1:​MLST8:​MTOR|​S2481_pho:​PROTOR*:​RAC1:​RICTOR@Lipid Raft map → map DEPTOR:​MAPKAP1:​MLST8:​MTOR|​S2481_pho:​PROTOR*:​RAC1:​RICTOR@Lipid Raft map
  5. DEPTOR@Cytoplasm map → map MLST8:​MTOR|​S1261_pho|​emp|​S2481_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map + DEPTOR:​MLST8:​MTOR|​S1261_pho|​emp|​S2481_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map
As Catalyser:
  1. gFOXP3@T_cell map → map rFOXP3@T_cell map
  2. gMYC@Cytosol map → map rMYC@Cytosol map
  3. IFNG@INNATE_IMMUNE_CELL_Cytosol map → map IFNG@default map
  4. GZMB@SECRETORY_GRANULE map → map GZMB@default map
  5. GZMA@SECRETORY_GRANULE map → map GZMA@default map
  6. gIL10@INNATE_IMMUNE_CELL_Cytosol map → map rIL10@INNATE_IMMUNE_CELL_Cytosol map
  7. MLST8:​MTOR|​S1261_pho|​emp|​S2481_pho:​PRAS40*|​S183_pho|​T246_pho|​S212_pho|​S221_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map → map MLST8:​MTOR|​S1261_pho|​emp|​S2481_pho:​RAC1:​RPTOR|​S696_pho|​T706_pho|​S855_pho|​S863_pho|​S877_pho|​S859_pho@Membrane Lysosome map + PRAS40*|​S183_pho|​T246_pho|​S212_pho|​S221_pho@Membrane Lysosome map