Complex RHOA:ROCK* map
Complex composition:

  1. ROCK* map
  2. RHOA map

RHOA:​ROCK*@Cytoplasm

Identifiers
NAME:RHOA:ROCK*

References
s_wnc1_re141( Survival  map ):
Activated Daam1 is responisble for the inhibition
PMID:20351293
s_wnc1_re152( Survival  map ):
Binding of beta-arrestin to PTEN increases the lipid phosphatase activity of PTEN which converts PIP3 to PIP2. Active ROCK stimulates this complex formation
PMID:21642958
ROCK phosphorylates PTEN which is than activated. Activated PTEN reduces the concentration of PIP3
PMID:15793569
PMID:20008297

Modifications:
Participates in complexes:
In compartment: Cytoplasm
  1. RHOA:​ROCK*@Cytoplasm map
Participates in reactions:
As Reactant or Product:
  1. RHOA:​ROCK*@Cytoplasm map → map Proliferation@Nucleus map
  2. RHOA:​ROCK*@Cytoplasm map → map Cell migration@Nucleus map
  3. RHOA:​ROCK*@Cytoplasm map → map Centrosome positioning@Nucleus map
  4. RHOA:​ROCK*@Cytoplasm map → map Actin polymerization@Nucleus map
  5. RHOA@Cytoplasm map + ROCK*@Cytoplasm map → map RHOA:​ROCK*@Cytoplasm map
  6. RHOA:​ROCK*@Cytoplasm map → map Microtubules@Cytoplasm map
  7. RHOA:​ROCK*@Cytoplasm map → map Cell contraction@Cytoplasm map
As Catalyser:
  1. _beta_-Arrestin*@Cytoplasm map + PTEN@Cytoplasm map → map PTEN|​pho|​pho|​pho|​pho:​_beta_-Arrestin*@Cytoplasm map