Catalysis

1. RHOA:​ROCK*@Cytoplasm

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival   / WNT_NON_CANONICAL 

References
Binding of beta-arrestin to PTEN increases the lipid phosphatase activity of PTEN which converts PIP3 to PIP2. Active ROCK stimulates this complex formation
PMID:21642958
ROCK phosphorylates PTEN which is than activated. Activated PTEN reduces the concentration of PIP3
PMID:15793569
PMID:20008297