Phenotype Cell migration
Cell migration@Nucleus
References
s_wnc1_re142( Survival
):
Activated Daam1 is responisble for the inhibition
PMID:20351293
s_wnc1_re154( Survival
):
PTEN contains a C2-domain which inhibits cell migration. This inhibition works only when T383 is not phosphorylated
PMID:14976311
However, beta-arrestin can also bind PTEN in this C2-region thereby dis-inhibiting migration.
PMID:21642958
Cell migration@Cytoplasm
References
s_wca1_re75:( Survival
) PMID:17925383
Modifications:
In compartment: Cytoplasm
- Cell migration@Cytoplasm
In compartment: Nucleus
- Cell migration@Nucleus
Participates in complexes:
Participates in reactions:
As Reactant or Product:- APC:Microtubules@Cytoplasm
→
Cell migration@Cytoplasm
- RHOA:ROCK*@Cytoplasm
→
Cell migration@Nucleus
- PTEN|pho|pho|pho|pho:_beta_-Arrestin*@Cytoplasm
→
Cell migration@Nucleus
As Catalyser: