Protein IRF4 map

Identifiers
HUGO:IRF4

Maps_Modules
MODULE:MACROPHAGE
MODULE:IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS

References
PMID:20580461
IRF4 regulates expression of some IL4-dependent genes. IRF4 upregulates expression of CIITA, CYP1B1, CCL24, MPP6, and downregulate expression IL1RN.
PMID:16243976
IRF4 downregulates expression of TNFa, IL12p40, IL6 probably via inhibition of NF-kB and JNK signaling pathways.
PMID:12928384
M-CSF upregulates IFR3 protein level

IRF4@Cytosol

Identifiers

Maps_Modules

References

Modifications:
In compartment: Cytosol
  1. IRF4@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. rIRF4@Cytosol map → map IRF4@Cytosol map
    As Catalyser:
    1. gARG1@Cytosol map → map rARG1@Cytosol map
    2. rTNF@Cytosol map → map TNF@Cytosol map
    3. rMHC class II*@Cytosol map → map MHC class II*@Cytosol map
    4. rMRC1@Cytosol map → map MRC1@Cytosol map
    5. gCIITA@Cytosol map → map rCIITA@Cytosol map
    6. gCYP1B1@Cytosol map → map rCYP1B1@Cytosol map
    7. gCCL24@Cytosol map → map rCCL24@Cytosol map
    8. gMPP6@Cytosol map → map rMPP6@Cytosol map
    9. gIL1RN@Cytosol map → map rIL1RN@Cytosol map
    10. IFNGR1@Membrane map + IFNGR2@Membrane map → map IFNGR1:​IFNGR2@Membrane map
    11. rCD40@Cytosol map → map CD40@Membrane map
    12. rCD80@Cytosol map → map CD80@Membrane map
    13. rCD86@Cytosol map → map CD86@Membrane map
    14. gIL12p40*@Cytosol map → map rIL12p40*@Cytosol map
    15. gIL6@Cytosol map → map rIL6@Cytosol map