Complex IFNGR1:IFNGR2 map
Complex composition:

  1. IFNGR2 map
  2. IFNGR1 map

IFNGR1:​IFNGR2@Membrane

Identifiers
NAME:IFNGR1:IFNGR2

Maps_Modules
MODULE:MACROPHAGE

References
PMID:17683974
IFNG dimer binds to receptor contained two IFNGR1 and two IFNGR2 subunits.
PMID: 19833085
IFNG receptor is assosiated with kinases JAK1 and JAK2.
Ligand engagement of the IFNG receptor leads to activation of receptor-associated Jak1 and Jak2 and phosphorylation of a receptor tyrosine residue
(Y440) that serves as a docking site for STAT1, which exists in a latent state in the cytoplasm.

Modifications:
Participates in complexes:
In compartment: Membrane
  1. IFNGR1:​IFNGR2@Membrane map
Participates in reactions:
As Reactant or Product:
  1. IFNGR1@Membrane map + IFNGR2@Membrane map → map IFNGR1:​IFNGR2@Membrane map
  2. JAK2@Cytosol map + JAK1@Cytosol map + IFNGR1:​IFNGR2@Membrane map + IFNG|​hm2@default map → map IFNGR1|​pho:​IFNGR2:​IFNG|​hm2:​JAK1:​JAK2@Membrane map
As Catalyser: