Protein TNFR2* map

Identifiers
HUGO:TNFRSF1B

Maps_Modules
MODULE:MACROPHAGE
MODULE:IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS

References
PMID:21133840, PMID:24378531
TNF acts through two transmembrane receptors: TNF receptor 1 (TNFR1), also known as p55 or p60, and TNF receptor 2 (TNFR2), also known as p75 or p80. Macrophages are reported to express both receptors.

TNFR2*@Membrane

Identifiers

Maps_Modules

References

Modifications:
In compartment: Membrane
  1. TNFR2*@Membrane map
Participates in complexes:
In compartment: Membrane
  1. TNF:​TNFR2*:​TRAF1:​TRAF2@Membrane map
Participates in reactions:
As Reactant or Product:
  1. TNF@default map + TNFR2*@Membrane map + TRAF1@Cytosol map + TRAF2@Cytosol map → map TNF:​TNFR2*:​TRAF1:​TRAF2@Membrane map
As Catalyser:
  1. JUN@Cytosol map → map JUN|​pho|​active@Cytosol map
  2. NFKBIA|​pho@Cytosol map → map degraded
  3. gIRF1@Cytosol map → map rIRF1@Cytosol map
  4. JNK*@Cytosol map → map JNK*|​pho|​active@Cytosol map
  5. TRAF2@Cytosol map → map degraded
  6. p38*@Cytosol map → map p38*|​pho|​active@Cytosol map