Protein HK2 map

Identifiers
HUGO:HK2
hexokinase 2
HUGO:HK2 hgnc_id:HGNC:4923 HGNC:4923 ENTREZ:3099 UNIPROT:P52789

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / METABOLIC  map
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / MITOCHONDRIAL_PERMEABILITY_TRANSITION  map
 Regulated Cell Death  map  / MOMP_REGULATION  map
 RECON2  map

References
PMID:25732824
Hexokinase 2 is upregulated in CAFs downstream of HIF1A
PMID:9436976
HK2 is a dicrect target of HIF1A
PMID:15033708
PMID:18309324
PMID:25486353

Modifications:
In compartment: Cytosol
  1. HK2@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. rHK2@Cytosol map → map HK2@Cytosol map
    2. rHK2@Nucleus map → map HK2@Cytosol map
    3. HK2@Cytosol map → map HK*@Cytosol map
    As Catalyser:
    1. glucose@Cytosol map → map Glycolysis@Cytosol map
    2. glucose@Cytosol map + ATP@Cytosol map → map glucose-6P@Cytosol map + ADP@Cytosol map