Identifiers
HUGO:HK2
hexokinase 2
HUGO:HK2 HGNC:4923 ENTREZ:3099 UNIPROT:P52789
Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
Cancer Associated Fibroblasts
/ METABOLIC
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
Regulated Cell Death
/ APOPTOSIS
Regulated Cell Death
/ STARVATION_AUTOPHAGY
Regulated Cell Death
/ GLUCOSE_METABOLISM
Regulated Cell Death
/ MITOCHONDRIAL_METABOLISM
Regulated Cell Death
/ MOMP_REGULATION
Regulated Cell Death
/ NECROPTOSIS
References
PMID:25732824
Hexokinase 2 is upregulated in CAFs downstream of HIF1A
PMID:9436976
HK2 id e dicrect target of HIF1A
Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
Regulated Cell Death
/ APOPTOSIS
Regulated Cell Death
/ STARVATION_AUTOPHAGY
Regulated Cell Death
/ GLUCOSE_METABOLISM
Regulated Cell Death
/ MITOCHONDRIAL_METABOLISM
Regulated Cell Death
/ MOMP_REGULATION
Regulated Cell Death
/ NECROPTOSIS
References
rc_re158( Regulated Cell Death
):
Reaction (id=re340, name=; 10 01 04.xml)
PMID:11557773
by HIF1
PMID:14672622
in liver tumors by HIF1
PMID:16782875
by MLX:MLXIP