Antisense RNA MIR20A map

Identifiers
microRNA 20a
HUGO:MIR20A HGNC:31577 ENTREZ:406982
HUGO:MIR20A
HUGO:MIR20A HGNC:31577 ENTREZ:406982 GENECARDS:MIR20A KEGG:406982 ATLASONC:GC_MIR20A WIKI:MIR20A

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
 Innate Immunity  map  / IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS  map
 Innate Immunity  map  / MIRNA_TF_IMMUNOSUPPRESSIVE  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / HEDGEHOG  map

References
 NATURAL_KILLER  map
PMID:25277195, PMID:24813230
Inhibition of MIR20A or MIR93 upregulates translation of their predicted targets (MICA, MICB, ULBP2 or ULBP3) in tumor cells and upregulates NK cytotoxicity against these cells.
PMID:21383238
Both miR-17-5p and miR-20a alleviate suppressive potential of myeloid-derived suppressor cells and macrophages by modulating STAT3 expression.
PMID:20851997

arMIR20A@Cytosol

References
rc_re147:( Regulated Cell Death  map ) PMID:15136036
rc_re148( Regulated Cell Death  map ):
PMID:15944709
MIR20A and MIR17 repress E2F1. MYC, through MIR17 and MIR20A, inactivates E2F1 at the post-transcriptional level.

arMIR20A@Nucleus

References
s_shh2_re136:( Survival  map ) PMID:20851997 PMID:19351822
s_shh2_re153:( Survival  map ) PMID:21383238
s_shh2_re155:( Survival  map ) PMID:18695042

Modifications:
In compartment: Cytosol
  1. arMIR20A@Cytosol map
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. arMIR20A@INNATE_IMMUNE_CELL_Cytosol map
In compartment: Nucleus
  1. arMIR20A@Nucleus map
In compartment: TUMOR_CELL_AS_INDUCTOR
  1. arMIR20A@TUMOR_CELL_AS_INDUCTOR map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. MIR20A:​STAT3@INNATE_IMMUNE_CELL_Cytosol map
In compartment: Nucleus
  1. MIR20A:​STAT3@Nucleus map
  2. CyclinD*:​MIR20A@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. rSTAT3@INNATE_IMMUNE_CELL_Cytosol map + arMIR20A@INNATE_IMMUNE_CELL_Cytosol map → map MIR20A:​STAT3@INNATE_IMMUNE_CELL_Cytosol map
  2. MIR20A:​STAT3@INNATE_IMMUNE_CELL_Cytosol map → map degraded
  3. arMIR17-92*@Nucleus map → map arMIR17@Cytosol map + arMIR18A@Cytosol map + arMIR19A@Cytosol map + arMIR20A@Cytosol map + arMIR19B1@Cytosol map + arMIR92A1@Cytosol map
  4. gMIR17-92*@Nucleus map → map arMIR20A@Nucleus map
  5. arMIR20A@Nucleus map + rSTAT3@Nucleus map → map MIR20A:​STAT3@Nucleus map
  6. arMIR20A@Nucleus map + rCyclinD*@Nucleus map → map CyclinD*:​MIR20A@Nucleus map
As Catalyser:
  1. rULBP2@TUMOR_CELL_AS_INDUCTOR map → map ULBP2@TUMOR_CELL_AS_INDUCTOR map
  2. rMICA@TUMOR_CELL_AS_INDUCTOR map → map MICA@TUMOR_CELL_AS_INDUCTOR map
  3. rMICB@TUMOR_CELL_AS_INDUCTOR map → map MICB@TUMOR_CELL_AS_INDUCTOR map
  4. rUDLP3@TUMOR_CELL_AS_INDUCTOR map → map ULBP3@TUMOR_CELL_AS_INDUCTOR map
  5. rE2F1@Nucleus map → map E2F1@Nucleus map
  6. rFAS@Nucleus map → map FAS@Cytosol map