Antisense RNA MIR17 map

Identifiers
microRNA 17
HUGO:MIR17 HGNC:31547 ENTREZ:406952
HUGO:MIR17

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
 Innate Immunity  map  / IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS  map
 Innate Immunity  map  / MIRNA_TF_IMMUNOSUPPRESSIVE  map

References
synonym:MIR-17-92
 MACROPHAGE  map
 MDSC  map
PMID:21383238
Both miR-17-5p and miR-20a alleviate suppressive potential of myeloid-derived suppressor cells and macrophages by modulating STAT3 expression.

arMIR17@Nucleus

References
mo_re191:( motility  map ) PMID:22677902

arMIR17@Cytosol

References
rc_re147:( Regulated Cell Death  map ) PMID:15136036
rc_re148( Regulated Cell Death  map ):
PMID:15944709
MIR20A and MIR17 repress E2F1. MYC, through MIR17 and MIR20A, inactivates E2F1 at the post-transcriptional level.

Modifications:
In compartment: Cytosol
  1. arMIR17@Cytosol map
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. arMIR17@INNATE_IMMUNE_CELL_Cytosol map
In compartment: Nucleus
  1. arMIR17@Nucleus map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. MIR17:​STAT3@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. rSTAT3@INNATE_IMMUNE_CELL_Cytosol map + arMIR17@INNATE_IMMUNE_CELL_Cytosol map → map MIR17:​STAT3@INNATE_IMMUNE_CELL_Cytosol map
  2. MIR17:​STAT3@INNATE_IMMUNE_CELL_Cytosol map → map degraded
  3. gMIR17@Nucleus map → map arMIR17@Nucleus map
  4. arMIR17-92*@Nucleus map → map arMIR17@Cytosol map + arMIR18A@Cytosol map + arMIR19A@Cytosol map + arMIR20A@Cytosol map + arMIR19B1@Cytosol map + arMIR92A1@Cytosol map
As Catalyser:
  1. rE2F1@Nucleus map → map E2F1@Nucleus map