Complex CRB3:PALS1* map
Complex composition:

  1. PALS1* map
  2. CRB3 map

CRB3:​PALS1*@Cytosol

Identifiers
NAME:CRB3:PALS1*

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / CELL_CELL_ADHESIONS  map
 EMT Senescence  map  / CYTOSKELETON_POLARITY  map

References
PMID:8365569
PMID:18005931
PMID:11740559
PMID:11740560
CRB3 and PALS1* in the same pathway
PALS1* binds to CRB3 via its PDZ domain
em_emtc_emtc_re96( EMT Senescence  map ):
PMID:10102271
PATJ* is a component of the Crb complex. The L27 domain of PATJ* binds to the L27 domain of PALS1*
PMID:11927608
PALS1 contains two L27 domains, 1 PDZ domain, 1 SH3 domain, 1 inactive Guanylate kinase domain
Interaction PALS1-LIN7 via the C-terminal L27 domain of PALS1
PMID:10871881
LIN7 contains one L27 domain, 1 PDZ domain
PMID:18177979
Lin7 is a component of the Crumbs complex in Drosophila epithelia and photoreceptor cells
PMID:2288140
Apical recuritment of PATJ* and LIN7 depends on the CRB3/PALS1* complex
em_emtc_emtc_re113( EMT Senescence  map ):
Without PALS1 (Sdt in Drosophila), CRB is delivered to the apical plasma membrane but rapidly endocytosed and degraded
The complex PALS1-CRB hence stabilizes CRB

Modifications:
Participates in complexes:
In compartment: Cytosol
  1. CRB3:​PALS1*@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. CRB3:​PALS1*@Cytosol map → map CRB3@Cytosol map
  2. CRB3@Cytosol map + PALS1*@Cytosol map → map CRB3:​PALS1*@Cytosol map
  3. PATJ*@Cytosol map + CRB3:​PALS1*@Cytosol map + LIN7C@Cytosol map → map CRB3:​LIN7C:​PALS1*:​PATJ*@Cytosol map
As Catalyser: