Complex PLCG1:RTK*:SRC map
Complex composition:

  1. SRC map
  2. PLCG1 map
  3. RTK* map

PLCG1:​RTK*:​SRC@Plasma Membrane

Identifiers
NAME:PLCG1:RTK*:SRC

References
su_mpk1_mpk1_re41( Survival  map ):
Among the signalling molecules recruited to phosphorylated LAT is PLCG.
Shp-2 (not modelled) contributes to Ras signalling from the Golgi by stimulating the activation of Src family of kinases and in turn their substrate PLCG.
PMID:16488589 PMID:17496910
su_mpk1_mpk1_re45( Survival  map ):
PLCG acts on PIP2 in the PM to produce DAG and IP3.
PMID:16488589
IP3 diffuses through the cytosol and binds to receptors on the endoplasmic reticulum causing the release of calcium ions (Ca2+) into the cytosol.
http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/S/Second_messengers.html

Modifications:
Participates in complexes:
In compartment: Plasma Membrane
  1. PLCG1:​RTK*:​SRC@Plasma Membrane map
Participates in reactions:
As Reactant or Product:
  1. RTK*:​SRC@Plasma Membrane map + PLCG1@Cytoplasm map → map PLCG1:​RTK*:​SRC@Plasma Membrane map
As Catalyser:
  1. PIP2@Plasma Membrane map → map IP3@Endoplasmic Reticulum map + DAG@Plasma Membrane map