Reaction dissociation su_mpk1_mpk1_re45 map

PIP2@Plasma Membrane map → IP3@Endoplasmic Reticulum map + DAG@Plasma Membrane map

Reaction regulators:
Catalysis
  1. PLCG1:​RTK*:​SRC@Plasma Membrane map


References
PLCG acts on PIP2 in the PM to produce DAG and IP3.
PMID:16488589
IP3 diffuses through the cytosol and binds to receptors on the endoplasmic reticulum causing the release of calcium ions (Ca2+) into the cytosol.
http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/S/Second_messengers.html