Protein TNFRSF1B map

Identifiers
tumor necrosis factor receptor superfamily member 1B
TNFR2
HUGO:TNFRSF1B HGNC:11917 ENTREZ:7133 UNIPROT:P20333

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / MAPK  map

References
Upon ligand-induced TNFR1 trimerisation (not modelled) the TNFR1 death domain binds the death domain of the platform adapter protein TRADD. In contrast TNFR2 does not possess a death domain and instead binds directly to TRAF proteins (TRAF2).
PMID:11274345

TNFRSF1B@Plasma Membrane

References
su_mpk1_mpk1_re124( Survival  map ):
Upon ligand-induced TNFR1 trimerisation (not modelled) the TNFR1 death domain binds the death domain of the platform adapter protein TRADD. In contrast TNFR2 does not possess a death domain and instead binds directly to TRAF proteins (TRAF2).
PMID:11274345

Modifications:
In compartment: Plasma Membrane
  1. TNFRSF1B@Plasma Membrane map
Participates in complexes:
In compartment: Cytoplasm
  1. TAK1*|​pho:​TNFRSF1B:​TRAF2@Cytoplasm map
  2. MAP3K1|​pho:​TNFRSF1B:​TRAF2@Cytoplasm map
  3. MAP3K5|​pho:​TNFRSF1B:​TRAF2@Cytoplasm map
  4. MAP3K2_3*|​pho:​TNFRSF1B:​TRAF2@Cytoplasm map
In compartment: Plasma Membrane
  1. TNFRSF1B:​TRAF2@Plasma Membrane map
Participates in reactions:
As Reactant or Product:
  1. TRAF2@Cytoplasm map + TNFRSF1B@Plasma Membrane map → map TNFRSF1B:​TRAF2@Plasma Membrane map
  2. TNFRSF1B:​TRAF2@Plasma Membrane map + TAK1*@Cytoplasm map → map TAK1*|​pho:​TNFRSF1B:​TRAF2@Cytoplasm map
  3. MAP3K1@Cytoplasm map + TNFRSF1B:​TRAF2@Plasma Membrane map → map MAP3K1|​pho:​TNFRSF1B:​TRAF2@Cytoplasm map
  4. MAP3K2_3*@Cytoplasm map + TNFRSF1B:​TRAF2@Plasma Membrane map → map MAP3K2_3*|​pho:​TNFRSF1B:​TRAF2@Cytoplasm map
  5. TNFRSF1B:​TRAF2@Plasma Membrane map → map ROS@Cytoplasm map
  6. TNFRSF1B:​TRAF2@Plasma Membrane map + MAP3K5@Cytoplasm map → map MAP3K5|​pho:​TNFRSF1B:​TRAF2@Cytoplasm map
As Catalyser:
  1. MAP2K4@Cytoplasm map → map MAP2K4|​pho|​pho@Cytoplasm map
  2. MAP2K3@Cytoplasm map → map MAP2K3|​pho|​pho@Cytoplasm map
  3. MAP2K7@Cytoplasm map → map MAP2K7|​pho|​pho@Cytoplasm map
  4. MAP2K6@Cytoplasm map → map MAP2K6|​pho|​pho@Cytoplasm map
  5. MEK*@Cytoplasm map → map MEK*|​pho|​pho@Cytoplasm map