Protein MAP3K2_3* map

Identifiers
mitogen-activated protein kinase kinase kinase 2
MEKK2
HUGO:MAP3K2 HGNC:6854 ENTREZ:10746 UNIPROT:Q9Y2U5
mitogen-activated protein kinase kinase kinase 3
MEKK3
HUGO:MAP3K3 HGNC:6855 ENTREZ:4215 UNIPROT:Q99759

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / MAPK  map

References
MEKK2 and MEKK3 can activate JNK P38 and ERK pathways
PMID:11274345

MAP3K2_3*@Cytoplasm

References
su_mpk1_mpk1_re140:( Survival  map ) Activation of MEKK2 and MEKK3 is assumed to follow the same mechanisms of MEKK1 activation

Modifications:
In compartment: Cytoplasm
  1. MAP3K2_3*@Cytoplasm map
Participates in complexes:
In compartment: Cytoplasm
  1. MAP3K2_3*|​pho:​TNFRSF1B:​TRAF2@Cytoplasm map
  2. MAP3K2_3*|​pho:​RIPK1:​TNFRSF1A:​TRADD:​TRAF2@Cytoplasm map
  3. GRB2:​MAP3K2_3*|​pho:​RAS*|​pho:​RTK*:​SOS*@Cytoplasm map
Participates in reactions:
As Reactant or Product:
  1. GRB2:​RAS*|​pho:​RTK*:​SOS*@Plasma Membrane map + MAP3K2_3*@Cytoplasm map → map GRB2:​MAP3K2_3*|​pho:​RAS*|​pho:​RTK*:​SOS*@Cytoplasm map
  2. MAP3K2_3*@Cytoplasm map + RIPK1:​TNFRSF1A:​TRADD:​TRAF2@Plasma Membrane map → map MAP3K2_3*|​pho:​RIPK1:​TNFRSF1A:​TRADD:​TRAF2@Cytoplasm map
  3. MAP3K2_3*@Cytoplasm map + TNFRSF1B:​TRAF2@Plasma Membrane map → map MAP3K2_3*|​pho:​TNFRSF1B:​TRAF2@Cytoplasm map
As Catalyser:
  1. MAP2K4@Cytoplasm map → map MAP2K4|​pho|​pho@Cytoplasm map
  2. MAP2K7@Cytoplasm map → map MAP2K7|​pho|​pho@Cytoplasm map
  3. MAP2K6@Cytoplasm map → map MAP2K6|​pho|​pho@Cytoplasm map
  4. MEK*@Cytoplasm map → map MEK*|​pho|​pho@Cytoplasm map