Protein TSPO
Identifiers
HUGO:TPSO
synonyms:peripheral benzodiazepine receptor,PBR
Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
Regulated Cell Death
/ MITOCHONDRIAL_PERMEABILITY_TRANSITION
Regulated Cell Death
/ MOMP_REGULATION
References
PMID:15033708
PMID:18309324
PMID:25486353
Modifications:
In compartment: Mitochondria
- TSPO@Mitochondria
Participates in complexes:
In compartment: Mitochondrial inner membrane
- (ANT*:CK*:HK*:PPID:TSPO:VDAC*)|active@Mitochondrial inner membrane
Participates in reactions:
As Reactant or Product:- (ANT*:CK*:HK*:PPID:TSPO:VDAC*)|active@Mitochondrial inner membrane
→
(ANT*:CK*:HK*:PPID:TSPO:VDAC*)|active@Mitochondrial inner membrane
- (ANT*:CK*:HK*:PPID:TSPO:VDAC*)|active@Mitochondrial inner membrane
→
MOMP@Mitochondrial inner membrane
- VDAC*@Mitochondria
+ ANT*@Mitochondrial inner membrane
+ PPID@Mitochondria
+ CK*@Mitochondria
+ HK*@Cytosol
+ TSPO@Mitochondria
→
(ANT*:CK*:HK*:PPID:TSPO:VDAC*)|active@Mitochondrial inner membrane
- (ANT*:CK*:HK*:PPID:TSPO:VDAC*)|active@Mitochondrial inner membrane
→
ROS Production@Cytosol
As Catalyser:- cleaved~AIFM1*@Mitochondrial inner membrane
→
cleaved~AIFM1*@Cytosol