Protein CAPN2
Identifiers
calpain 2, (m/II) large subunit
HUGO:CAPN2 HGNC:1479 ENTREZ:824 UNIPROT:P17655
Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
Regulated Cell Death
/ APOPTOSIS
Regulated Cell Death
/ CASPASES
Regulated Cell Death
/ DEATH_RECEPTOR_PATHWAYS
Regulated Cell Death
/ MOMP_REGULATION
Regulated Cell Death
/ MITOCHONDRIAL_PERMEABILITY_TRANSITION
References
synonym:m-calpain
Modifications:
Participates in complexes:
In compartment: Cytosol
- CAPN2:Ca2+_@Cytosol
Participates in reactions:
As Reactant or Product:- XIAP|S87_unk@Cytosol
→
CAPN2:Ca2+_@Cytosol
As Catalyser:- BAX@Cytosol
→
cleaved BAX*@Cytosol
- VDAC*@Mitochondria
→
degraded
- p53*|S15_unk@Cytosol
→
degraded
- BAX|S163_unk|T167_unk@Mitochondrial inner membrane
→
cleaved BAX*@Mitochondrial inner membrane
- Caspase9*|S196_unk|T125_unk|S144_unk|Y153_unk@Cytosol
→
degraded
- BID|unk@Cytosol
→
cleaved_BID*@Cytosol
- XIAP|ubi@Cytosol
→
degraded