Phenotype MIGRATION_INTO_THE_TUMOR map
MIGRATION_INTO_THE_TUMOR@default

References
PMID:12118074 , PMID:3491869
p38 mitogen-activated protein kinase is required for TGF??-mediated fibroblastic transdifferentiation and cell migration
PMID:23505219
Platelet-derived growth factor-D and Rho GTPases regulate recruitment of cancer-associated fibroblasts in cholangiocarcinoma
In fibroblasts, PDGF-D activated the Rac1 and Cdc42 Rho GTPases and c-Jun N-terminal kinase (JNK). Selective inhibition of Rho GTPases (particularly Rac1) and of JNK strongly reduced PDGF-D-induced fibroblast migration.
PMID:20861157
MIF inhibits in CXCR2/CD74-dependent manner recruitment of CAFs to the growing tumor.

Modifications:
In compartment: default
  1. MIGRATION_INTO_THE_TUMOR@default map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. TGFB*@default map → map MIGRATION_INTO_THE_TUMOR@default map
    2. MIF@default map → map MIGRATION_INTO_THE_TUMOR@default map
    3. AKT*|​pho|​active@Cytosol map → map MIGRATION_INTO_THE_TUMOR@default map
    4. Actomyosin_contractility@default map → map MIGRATION_INTO_THE_TUMOR@default map
    5. PDGF*@default map → map MIGRATION_INTO_THE_TUMOR@default map
    6. Microtubule_polymerization@Cytosol map → map MIGRATION_INTO_THE_TUMOR@default map
    7. FRS2|​pho|​active@Cytosol map → map MIGRATION_INTO_THE_TUMOR@default map
    8. WNT7@default map → map MIGRATION_INTO_THE_TUMOR@default map
    9. Septins_polymerization@Cytosol map → map MIGRATION_INTO_THE_TUMOR@default map
    As Catalyser: