Protein WNT7 map

Identifiers
HUGO:WNT7

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / GROWTH_FACTORS_SIGNALING_PATHWAYS  map

References
PMID:26777421
Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness.
Wnt7a does not signal through the classical Wnt pathways to trigger CAF conversion but potentiates TGF?? receptor signalling.

Modifications:
In compartment: default
  1. WNT7@default map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. WNT7@default map → map MIGRATION_INTO_THE_TUMOR@default map
    2. WNT7@default map → map TUMOR_INVASION@default map
    As Catalyser:
    1. TGFBR1@Cytosol map + TGFBR2@Cytosol map + TGFB*@default map → map TGFB*:​TGFBR1:​TGFBR2@Cytosol map