Complex GAB1:GRB2 map
Complex composition:

  1. GRB2 map
  2. GAB1 map

GAB1:​GRB2@Cytoplasm

Identifiers
NAME:GAB1:GRB2

References
su_mpk1_mpk1_re287( Survival  map ):
Grb2 recruits the docking protein Gab1 which is tyrosine phosphorylated by EGFR or FGFR leading to recruitment and activation of the PI3K-Akt cell survival pathway.
PMID:15567848
su_mpk1_mpk1_re284( Survival  map ):
Recruitment of PI 3-kinase by Gab1 results in a positive-feedback loop mediated by binding of the PH domain of Gab1 to the product of PI3-kinase activation phosphatidylinositol-345-triphosphate.
PMID:15567848 PMID:15199124

GAB1|​pho:​GRB2@Cytoplasm

Identifiers
NAME:GAB1:GRB2

References
su_mpk1_mpk1_re284( Survival  map ):
Grb2 recruits the docking protein Gab1 which is tyrosine phosphorylated by EGFR or FGFR leading to recruitment and activation of the PI3K-Akt cell survival pathway.
Recruitment of PI 3-kinase by Gab1 results in a positive-feedback loop mediated by binding of the PH domain of Gab1 to the product of PI3-kinase activation phosphatidylinositol-345-triphosphate.
PMID:15567848 PMID:15199124
su_mpk1_mpk1_re265( Survival  map ):
Grb2 recruits the docking protein Gab1 which is tyrosine phosphorylated by FGFR leading to recruitment and activation of the PI3K-Akt cell survival pathway.
PMID:15567848

Modifications:
Participates in complexes:
In compartment: Cytoplasm
  1. GAB1:​GRB2@Cytoplasm map
  2. GAB1|​pho:​GRB2@Cytoplasm map
Participates in reactions:
As Reactant or Product:
  1. GAB1:​GRB2@Cytoplasm map → map GAB1|​pho:​GRB2@Cytoplasm map
  2. GRB2@Cytoplasm map + GAB1@Cytoplasm map → map GAB1:​GRB2@Cytoplasm map
As Catalyser:
  1. p110*@Cytoplasm map → map p110*|​pho@Cytoplasm map