Identifiers
NAME:Ku70*:Ku80*:Securin*
Maps_Modules
HMC:GENOME_INSTABILITY_AND_MUTATION
Cell Cycle DNA Repair / C_NHEJ
References
PMID:17962814
ce_re374( Cell Cycle DNA Repair ):
Link between spindle checkpoint and ds break DNA repair pathway (C_NHEJ)
ce_re80( Cell Cycle DNA Repair ):
The complex MRN:BRCA1:phos-Ub-CtIP is central in the shift toward HR, because it activates resection for HR and blocks Ku70/80 of C_NHEJ:
PMID:19357644, PMID:15485915, PMID:19490890, PMID:18716619 (for CDK-dep phosph), PMID:20051983