Complex IL1R1:IRAK1:MYD88:TRAF6 map
Complex composition:

  1. MYD88 map
  2. IRAK1 map
  3. TRAF6 map
  4. IL1R1 map

IL1R1:​IRAK1:​MYD88:​TRAF6@Plasma Membrane

Identifiers
NAME:IL1R1:IRAK1:MYD88:TRAF6

References
su_mpk1_mpk1_re128( Survival  map ):
Upon recruitment to the IL-1R complex IRAK1 binds TRAF6 forming a MyD88-IRAK1-TRAF6 complex analogous to the TNFR-associated complex of TRADD RIP and TRAF2.
PMID:11274345
su_mpk1_mpk1_re131( Survival  map ):
Endogenous TAK1 is activated by TGF-beta IL-1 and TNF.

Modifications:
Participates in complexes:
In compartment: Plasma Membrane
  1. IL1R1:​IRAK1:​MYD88:​TRAF6@Plasma Membrane map
Participates in reactions:
As Reactant or Product:
  1. TRAF6@Cytoplasm map + IL1R1:​IRAK1:​MYD88@Plasma Membrane map → map IL1R1:​IRAK1:​MYD88:​TRAF6@Plasma Membrane map
  2. TAK1*@Cytoplasm map + IL1R1:​IRAK1:​MYD88:​TRAF6@Plasma Membrane map → map IL1R1:​IRAK1:​MYD88:​TAK1*|​pho:​TRAF6@Cytoplasm map
As Catalyser: