+ IL1R1:IRAK1:MYD88@Plasma Membrane → IL1R1:IRAK1:MYD88:TRAF6@Plasma Membrane References
Upon recruitment to the IL-1R complex IRAK1 binds TRAF6 forming a MyD88-IRAK1-TRAF6 complex analogous to the TNFR-associated complex of TRADD RIP and TRAF2.
PMID:11274345