Protein ABL1 map

Identifiers
c-abl oncogene 1, non-receptor tyrosine kinase
ABL, "c-abl oncogene 1, receptor tyrosine kinase", "v-abl Abelson murine leukemia viral oncogene homolog 1"
HUGO:ABL1 HGNC:76 ENTREZ:25 UNIPROT:P00519
ABL proto-oncongene 1, non receptor tyrosine-kinase
HUGO:ABL1
c-abl oncogene 1, receptor tyrosine kinase

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CELL_MATRIX_ADHESIONS  map
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
 Cell Cycle DNA Repair  map  / S_PHASE_CHECKPOINT  map
 Cell Cycle DNA Repair  map  / G2_M_CHECKPOINT  map
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / CASPASES  map
HMC:TUMOR_PROMOTING_INFLAMMATION
 Innate Immunity  map  / IMMUNOSUPPPRESSIVE_CORE_PATHWAYS  map

References
PMID:10837221
PMID:15459660, PMID:21435002, PMID:21199784, PMID:21051857
CASCADE:KIR2DL1
CASCADE:NKG2A
 NATURAL_KILLER  map
PMID:18835194
Association of CrkII with ALBL1(c-Abl) occurred during inhibition. ABL1 phosphorylates CRK and inhibits CRK activity downstream of KIR2DL1 and NKG2A/CD94 pathway..

ABL1|​S465_pho|​active@Nucleus

References
ce_re32:( Cell Cycle DNA Repair  map ) PMID:19788416, PMID:9168117, PMID:11804596
ce_re459:( Cell Cycle DNA Repair  map ) PMID:12709442, PMID:12628935, PMID:11971963

ABL1@Nucleus

References
ce_re32:( Cell Cycle DNA Repair  map ) PMID:19788416, PMID:9168117, PMID:11804596

Modifications:
In compartment: Cytosol
  1. ABL1@Cytosol map
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. ABL1@INNATE_IMMUNE_CELL_Cytosol map
In compartment: Nucleus
  1. ABL1@Nucleus map
  2. ABL1|​S465_pho|​active@Nucleus map
Participates in complexes:
In compartment: Cytosol
  1. ABL1:​TERT@Cytosol map
  2. ABL1:​TERT|​pho@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. ABL1@Nucleus map → map ABL1|​S465_pho|​active@Nucleus map
  2. Src family kinases*@Cytosol map → map ABL1@Cytosol map
  3. ABL1@INNATE_IMMUNE_CELL_Cytosol map → map ABL1@INNATE_IMMUNE_CELL_Cytosol map
  4. ABL1@Cytosol map → map cleaved~ABL1*@Cytosol map
  5. TERT@Cytosol map + ABL1@Cytosol map → map ABL1:​TERT@Cytosol map
  6. ABL1:​TERT@Cytosol map → map ABL1:​TERT|​pho@Cytosol map
As Catalyser:
  1. p53*@Nucleus map → map p53*|​pho|​ace|​active@Nucleus map
  2. RAD9*@Nucleus map → map RAD9*|​pho@Nucleus map
  3. p73*@Nucleus map → map p73*|​Y99_pho|​ace|​active@Nucleus map
  4. YAP1@Nucleus map → map YAP1|​pho@Nucleus map
  5. (BCAR1|​pho:​CBL|​pho:​CRK:​CRKL:​RAPGEF1)|​active@INNATE_IMMUNE_CELL_Cytosol map → map BCAR1|​pho:​CBL|​pho:​CRKL|​pho:​CRK|​pho:​RAPGEF1@INNATE_IMMUNE_CELL_Cytosol map
  6. ABL1:​TERT@Cytosol map → map ABL1:​TERT|​pho@Cytosol map