Complex PKA_C*:PKA_R*
Complex composition:
- PKA_R*
- PKA_C*
PKA_C*:PKA_R*@Cytoplasm
Identifiers
NAME:PKA_C*:PKA_R*
References
su_wnc1_s_wnc1_re44( Survival
):
PKA phosphorylates first Thr1548? followed by GSK3 at S1544
PMID:21406690
su_wnc1_s_wnc1_re93:( Survival
) PMID:21262972
(PKA_C*:PKA_R*)|active@Nucleus
Identifiers
NAME:PKA_C*:PKA_R*
References
s_wnc2_re85( Survival
):
S272 and S89 are PKA sites in NFAT3
PMID:10611249
(PKA_C*:PKA_R*)|active@Cytoplasm
Identifiers
NAME:PKA_C*:PKA_R*
References
s_wnc2_re4( Survival
):
PMID:21506126, PMID:21303971
Path to phosphorylation of b-catenin is not completely depicted here. For full paths see AKT-pathway
Activated CaSR inhibits phosphorylation of b-catenin, exact mechanism unknown
PMID:22094462
PKA_C*:PKA_R*@Cytoplasm
Identifiers
NAME:PKA_C*:PKA_R*
References
s_wca3_re82( Survival
):
High-cell density has positive influence on phosphorylation of APC by PKA thereby blocking nuclear import.
PMID:11689703
s_wca3_re101( Survival
):
References_begin
PMID:15649893
Modifications:
Participates in complexes:
In compartment: Cytoplasm
- PKA_C*:PKA_R*@Cytoplasm
- PKA_C*:PKA_R*@Cytoplasm
- (PKA_C*:PKA_R*)|active@Cytoplasm
In compartment: Nucleus
- (PKA_C*:PKA_R*)|active@Nucleus
Participates in reactions:
As Reactant or Product:- p38*@Cytoplasm
→
PKA_C*:PKA_R*@Cytoplasm
- High cell density@Cytoplasm
→
PKA_C*:PKA_R*@Cytoplasm
- PKA_C*:PKA_R*@Cytoplasm
→
PKA_C*:PKA_R*@Cytoplasm
As Catalyser:- APC@Cytoplasm
→
APC|S2054_pho@Cytoplasm
- LRP6@Cytoplasm
→
LRP6|S1544_pho|T1548_pho@Cytoplasm
- DACT1@Cytoplasm
→
DACT1|S237_pho|S827_pho@Cytoplasm
- _beta_-Catenin*@Cytoplasm
→
_beta_-Catenin*|S552_pho@Cytoplasm
- _beta_-Catenin*|S552_pho@Cytoplasm
→
_beta_-Catenin*|S552_pho|pho@Cytoplasm
- NFAT*@Nucleus
→
NFAT*|emp|S289_pho|S272_pho@Nucleus