Phenotype Autophagy death
Autophagy death@Cytosol
References
PMID:23846383
PMID:23774579
PMID:27754749
PMID:27048813
rc_re1829( Regulated Cell Death
):
Central to this outcome is the cell capacity to generate sufficient ATP and its ability to meet metabolic demands.
rc_re411( Regulated Cell Death
):
PMID:19818716
PMID:23030059
rc_re1779( Regulated Cell Death
):
PMID:22421439
PMID:28645028
rc_re1834( Regulated Cell Death
):
PMID:19838173
FLIP inhibits autophagy by competing with LC3 for binding of ATG3
Modifications:
In compartment: Cytosol
- Autophagy death@Cytosol
Participates in complexes:
Participates in reactions:
As Reactant or Product:- Lysosome fusing@Cytosol
→
Autophagy death@Cytosol
- Autophagy death@Cytosol
→
High ATP level@Cytosol
- Autophagy death@Cytosol
→
Phosphatidylserine exposure@Cytosol
- DRAM1@Cytosol
→
Autophagy death@Cytosol
- Autophagy survival@Cytosol
→
Autophagy death@Cytosol
- Unfolded Protein Response@Cytosol
→
Autophagy death@Cytosol
- Inadequation in ATP comsumption/production@Cytosol
→
Autophagy death@Cytosol
As Catalyser:- ATG3@Autopagosome
+ CFLAR@Cytosol
→
ATG3:CFLAR@Cytosol
- IKK_beta_*@Cytosol
→
IKK_beta_*|ubi@Cytosol