Phenotype Autophagy survival
Autophagy survival@Cytosol
References
PMID:23774579
Autophagy is induced in cells after many stressful situations such as starvation, hypoxia and infection, among others. Its finely tuned regulation is essential to maintain
cell and tissue homeostasis
PMID:19037093
PMID:23846383
PMID:20724831
PMID:27754749
PMID:27048813
rc_re1828( Regulated Cell Death
):
PMID:17446862
BAD reduces the extent of autophagy in response to starvation
rc_re1990( Regulated Cell Death
):
PMID:20424262
Ammonia derived from Glutaminolysis is a diffusible regulator of Autophagy
rc_re1829( Regulated Cell Death
):
Central to this outcome is the cell capacity to generate sufficient ATP and its ability to meet metabolic demands.
rc_re1838( Regulated Cell Death
):
PMID:23377657
PMID:23991959
Modifications:
In compartment: Cytosol
- Autophagy survival@Cytosol
Participates in complexes:
Participates in reactions:
As Reactant or Product:- Stress@Cytosol
→
Autophagy survival@Cytosol
- Nutrient starvation@Cytosol
→
Autophagy survival@Cytosol
- Autophagy survival@Cytosol
→
Autophagy death@Cytosol
- Autophagy survival@Cytosol
→
Protein and lipids degradation@Cytosol
- Autophagy survival@Cytosol
→
Energy production@Cytosol
- Autophagy survival@Cytosol
→
Lipolytic signal@Cytosol
- PARP1 overactivation@Nucleus
→
Autophagy survival@Cytosol
- Autophagy survival@Cytosol
→
Apoptotic death@Cytosol
- NH3@Cytosol
→
Autophagy survival@Cytosol
- NFKB1_p50*:RELA@Cytosol
→
Autophagy survival@Cytosol
- Autophagy survival@Cytosol
→
Survival@Cytosol
- Lysosome fusing@Cytosol
→
Autophagy survival@Cytosol
As Catalyser:- cleaved~Caspase8*@Autopagosome
→
degraded
- cleaved~Caspase8*@Cytosol
→
cleaved~Caspase8*@Autopagosome