Protein ATG3
Identifiers
autophagy related 3
HUGO:ATG3 HGNC:20962 ENTREZ:64422 UNIPROT:Q9NT62
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death
/ STARVATION_AUTOPHAGY
Regulated Cell Death
/ DEATH_RECEPTOR_PATHWAYS
References
PMID:23725295
PMID:23301705
PMID:23377657
PMID:24070470
ATG3@Autopagosome
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death
/ STARVATION_AUTOPHAGY
Regulated Cell Death
/ DEATH_RECEPTOR_PATHWAYS
References
rc_re1834( Regulated Cell Death
):
PMID:19838173
FLIP inhibits autophagy by competing with LC3 for binding of ATG3
rc_re1835( Regulated Cell Death
):
PMID:23377657
Cleavage of ATG3 by caspases
Modifications:
In compartment: Autopagosome
- ATG3@Autopagosome
Participates in complexes:
In compartment: Autopagosome
- ATG3:LC3-I*@Autopagosome
- ATG3:LC3-I*:Phosphatidyl ethanolamine@Autopagosome
In compartment: Cytosol
- ATG3:CFLAR@Cytosol
Participates in reactions:
As Reactant or Product:- ATG3@Autopagosome
+ LC3-I*@Autopagosome
→
ATG3:LC3-I*@Autopagosome
- ATG3:LC3-I*@Autopagosome
+ Phosphatidyl ethanolamine@Autopagosome
→
ATG3:LC3-I*:Phosphatidyl ethanolamine@Autopagosome
- ATG3:LC3-I*:Phosphatidyl ethanolamine@Autopagosome
→
ATG3:LC3-I*@Autopagosome
+ Phosphatidyl ethanolamine@Cytosol
- ATG3:LC3-I*:Phosphatidyl ethanolamine@Autopagosome
→
LC3*@Cytosol
- ATG3@Autopagosome
+ CFLAR@Cytosol
→
ATG3:CFLAR@Cytosol
- ATG3@Autopagosome
→
cleaved ATG3*@Autopagosome
As Catalyser:- Autophagosome formation@Autopagosome
→
Endosome fusing@Cytosol
- BNIP3L@Mitochondria
→
Mitophagy@Cytosol