Protein UNC5B map

Identifiers
unc-5 homolog B (C. elegans)
HUGO:UNC5B HGNC:12568 ENTREZ:219699 UNIPROT:Q8IZJ1

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / DEPENDANCE_RECEPTORS  map

References
PMID:20495383
PMID:19543238
PMID:12598906
p53RDL1 mediated p53-dependent apoptosis. Conversely, when p53RDL1 interacted with its ligand, Netrin-1, p53-dependent apoptosis was blocked
PMID:18582460

Modifications:
Participates in complexes:
In compartment: Cytosol
  1. CIP2A*:​DAPK1|​pho:​NTN1:​UNC5B@Cytosol map
  2. DAPK1|​emp:​PPP2CB:​PPPR1B:​UNC5B@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. CIP2A*:​DAPK1|​pho:​NTN1:​UNC5B@Cytosol map + PPP2CB:​PPPR1B@Cytosol map → map NTN1@Extracellular space map + DAPK1|​emp:​PPP2CB:​PPPR1B:​UNC5B@Cytosol map + CIP2A*@Cytosol map
  2. DAPK1|​emp:​PPP2CB:​PPPR1B:​UNC5B@Cytosol map → map cleaved UNC5B*@Cytosol map + DAPK1|​emp:​UNC5B-DD*@Cytosol map
As Catalyser: