Identifiers
KIAA1524
HUGO:KIAA1524 HGNC:29302 ENTREZ:57650 UNIPROT:Q8TCG1

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death   / DEATH_RECEPTOR_PATHWAYS 
 Regulated Cell Death   / DEPENDANCE_RECEPTORS 

References
PMID:21172653
CIP2A is an inhibitor of UNC5H2/B-induced DAPk activation

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death   / DEATH_RECEPTOR_PATHWAYS 
 Regulated Cell Death   / DEPENDANCE_RECEPTORS 

References
rc_re1693( Regulated Cell Death  ):
PMID:19543238
PMID:21172653
The UNC5H dependence receptors promote apoptosis in the absence of their ligand, netrin-1
in the absence of netrin-1, recruitment of PP2A to UNC5H2/B allows the activation of DAPk via a PP2A-mediated dephosphorylation

1. CIP2A*@Cytosol

1. CIP2A*:​DAPK1|​pho:​NTN1:​UNC5B@Cytosol

1. CIP2A*:​DAPK1|​pho:​NTN1:​UNC5B@Cytosol + PPP2CB:​PPPR1B@Cytosol → NTN1@Extracellular space + DAPK1|​emp:​PPP2CB:​PPPR1B:​UNC5B@Cytosol + CIP2A*@Cytosol